• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Visualization, Image-Guided Procedures pt.2; Progress in Biomedical Optics and Imaging; vol.8 no.28; Proceedings of SPIE-The International Society for Optical Engineering; vol.6509 pt.2 >The influence of CT based attenuation correction on PET/CT registration: an evaluation study
【24h】

The influence of CT based attenuation correction on PET/CT registration: an evaluation study

机译：基于CT的衰减校正对PET / CT配准的影响：一项评估研究

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We are currently developing a PET/CT based navigation system for guidance of biopsies and radiofrequency ablation (RFA) of early stage hepatic tumors. For these procedures, combined PET/CT data can potentially improve current interventions. The diagnostic efficacy of biopsies can potentially be improved by accurately targeting the region within the tumor that exhibits the highest metabolic activity. For RFA procedures the system can potentially enable treatment of early stage tumors, targeting tumors before structural abnormalities are clearly visible on CT. In both cases target definition is based on the metabolic data (PET), and navigation is based on the spatial data (CT), making the system highly dependent upon accurate spatial alignment between these data sets. In our institute all clinical data sets include three image volumes: one CT, and two PET volumes, with and without CT-based attenuation correction. This paper studies the effect of the CT-based attenuation correction on the registration process. From comparing the pairs of registrations from five data sets we observe that the point motion magnitude difference between registrations is on the same scale as the point motion magnitude in each one of the registrations, and that visual inspection cannot identify this discrepancy. We conclude that using non-rigid registration to align the PET and CT data sets is too variable, and most likely does not provide sufficient accuracy for interventional procedures.
机译：我们目前正在开发基于PET / CT的导航系统，以指导早期肝肿瘤的活检和射频消融（RFA）。对于这些程序，PET / CT组合数据可以潜在地改善当前的干预措施。通过准确地靶向肿瘤内表现出最高代谢活性的区域，可以潜在地提高活组织检查的诊断效力。对于RFA程序，该系统可以潜在地实现早期肿瘤的治疗，从而在CT上清晰可见结构异常之前就可以靶向肿瘤。在这两种情况下，目标定义均基于代谢数据（PET），导航基于空间数据（CT），这使得系统高度依赖于这些数据集之间的准确空间对齐。在我们研究所，所有临床数据集包括三个图像量：一个CT和两个PET量，带有和不带有基于CT的衰减校正。本文研究了基于CT的衰减校正对配准过程的影响。通过比较来自五个数据集的一对配准，我们观察到配准之间的点运动幅度差与每个配准中的点运动幅度处于相同的比例，并且目视检查无法识别出这种差异。我们得出的结论是，使用非刚性配准来对齐PET和CT数据集太易变，并且很可能无法为介入手术提供足够的准确性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号