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首页> 外文会议>Visualization, Image-Guided Procedures pt.2; Progress in Biomedical Optics and Imaging; vol.8 no.28; Proceedings of SPIE-The International Society for Optical Engineering; vol.6509 pt.2 >Evaluation of the Effect of Partial Asymmetric Stent Coverage on Neurovascular Aneurysm Hemodynamics Using Computer Fluid Dynamics (CFD) Calculations
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Evaluation of the Effect of Partial Asymmetric Stent Coverage on Neurovascular Aneurysm Hemodynamics Using Computer Fluid Dynamics (CFD) Calculations

机译：使用计算机流体动力学（CFD）计算评估部分不对称支架覆盖对神经血管瘤血流动力学的影响

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The asymmetric vascular stent (AVS) is a new minimally invasive endovascular device, designed to reduce the potential for further growth and rupture of cerebral aneurysms by substantially modifying the aneurysmal inflow. The low porosity part of the AVS or patch must be deployed to either completely or partially cover the aneurysm orifice. In this study, we investigated the effect on aneurysm hemodynamics of partial coverage with an asymmetric stent using Computational Fluid Dynamics (CFD) analysis and visualization. The low porosity patch of an asymmetric stent was computationally created and deformed to fit into the vessel lumen. Such a patch was placed both in an idealized aneurysm model and in a patient-specific aneurysm model to cover only a portion of the aneurysm orifice either proximally or distally according to the flow direction. The CFD-generated hemodynamic image sequences in the untreated and stented aneurysm models were compared. The asymmetric stent effectively attenuated the aneurysmal flow when the primary inflow was blocked by the patch. Consequently, the Wall Shear Stress (WSS) was reduced, and flow stasis was substantially increased by stenting. For the idealized model, distal placement was better for reducing the inflow jet, whereas for the patient-specific model proximal placement was better. We can conclude that CFD visualizations may be essential to guide either the optimal positioning of a small low porosity region of the AVS or the acceptability of inaccurate placement of a larger AVS patch for partial aneurysm orifice coverage.
机译：不对称血管支架（AVS）是一种新型的微创血管内装置，旨在通过实质性地改变动脉瘤的流入量来减少脑动脉瘤进一步生长和破裂的可能性。 AVS或贴剂的低孔隙率部分必须完全或部分覆盖动脉瘤孔口。在这项研究中，我们使用计算流体动力学（CFD）分析和可视化技术研究了不对称支架对部分覆盖的动脉瘤血液动力学的影响。通过计算创建了不对称支架的低孔隙斑块，并将其变形以适合血管内腔。将这样的贴片放置在理想​​的动脉瘤模型和患者特定的动脉瘤模型中，以根据流动方向仅覆盖近端或远端的一部分动脉瘤孔。比较了CFD生成的未治疗和支架动脉瘤模型中的血流动力学图像序列。当初次流入被斑块阻塞时，不对称支架有效地减弱了动脉瘤的流动。因此，通过置入支架可减少壁切应力（WSS），并显着增加血流淤滞。对于理想化模型，远端放置对减少流入射流更好，而对于特定于患者的模型，近端放置更好。我们可以得出结论，CFD可视化对于引导AVS的低孔隙率小区域的最佳定位或对于局部动脉瘤小孔覆盖不正确放置较大的AVS贴片的可接受性可能是必不可少的。

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