声明
摘要
Abstract
Contents
Abbreviations
Chapter one Introduction
Chapter two Materials and Methods
2．1 Population
2．1．1 Exclusion criteria
2．1．2 Included Patients
2．2 Clinical data
2．3 Prior to the procedure
2．3．1 Standard 12 lead electrocardiogram (ECG)
2．3．2 Measurement of P wave parameters
2．3．3 Standard 2D and Doppler echocardiography
2．3．4 Tissue Doppler Imaging
2．3．5 Radiofrequency catheter ablation procedure
2．4 Inter and intra observer reproducibility
2．5 Follow up
2．6 Control group
Chapter three Statistical analysis
Chapter four Results
4．1 Comparison between control and eases
4．2 Cases results
4．3 Comparison between persistent and paroxysmal AF patients
4．4 Receiver operating characteristic (ROC) of atrial conduction time，left atrial dyssynchrony time and P wave indices
4．5 Correlation between different cardiac parameters
4．6 Clinical predictors of AF recurrences
4．7 Improvement of dyssynchrony time after one year
Chapter Five Discussion
5．1 Atrial Dyssynchrony
5．2 How to measure atrial dyssynchrony
5．2．1 Invasive measurement of atrial dyssynchrony
5．2．2 Non invasive measurement of atrial dyssynehrony
5．2．3 Tissue Doppler echocardiography
5．2．4 Atrial dyssynchrony can also be assessed by strain imaging
5．3 Clinical practice of atrial dyssynchrony
5．4 Improvement of left atrial dyssynehrony after one year post ablation
5．5 P wave indices
5．6 Short and long term efficacy of ablation
5．7 Atrial resynchronization as a future method for improving atrial function
5．8 Atrial pacing
5．9 Molecular biology
Chapter six Conclusion
Chapter Seven Limitations
References
Review
Acknowledgement
Dedication
Personal Identity
Publications
