声明
INDEX
Synopsis
Acknowledgement
摘要
English Abstract
ABREVIATIONS AND ACRONYMS INDEX
Introduction
SURGICAL ANATOMY OF BREAST
MICROSCOPIC ANATOMY
BREAST DEVELOPMENT AND PHYSIOLOGY
EPIDEMIOLOGY OF BREAST CANCER
Aetological factors
Risk Factors of Breast Cancer
Pathology
Classification of primary Breast Cancer
Non-invasive Epithelial Cancers
Invasive Epithelial Cancers (percentage of total)
Molecular Markers and Breast Cancer Subtypes
Other Tumors of the Breast
DIAGNOSIS OF BREAST DISEASE
Patient History
Physical Examination
Biopsy
BREAST IMAGING
Screening Mammography
Ultrasonography
Magnetic Resonance Imaging
Nonpalpable Mammographic Abnormalities
Wire-Localized Surgical Excision
STAGING oF BREAST CANCER
TNM Classification for Breast Cancer (pathologic Staging)
Management／treatment
Surgery
Axillary surgery
Local recurrence
Radiotherapy
Adjuvant therapy
Hormone therapy
Chemotherapy
Breast reconstruction
Integrin αvβ6
Methods
Clinical samples
Antibodies and IHC
Immunohistochemical analysis and scoring
Statistical analysis
Results
The expression of integrin αvβ6 in breast cancer of China and Bangladesh
Association between clinicopathological characteristics and integrin αvβ6 expression
Correlation of integnn αvβ6 expression and overall sunrival in patients with breast cancer
Discussion
Expression of αvβ6 in Different Cancers
The Role of MMPs in αvβ6 Mediated cancer Progression
αvβ6 Integrin activate of TGF-β
RoIe of αvβ6 Integrin in Epithelial to Mesenchymal Transition
Role of Endocytosis in Cancer Progression
αvβ6 in Therapeutics of Cancer
Discussion result
Conclusion
References
