声明
Chapter 1. Introduction
Chapter 2. Literature review
2.1. Articular cartilage
2.2. Cartilage Function
2.2.1. Mechanical properties
2.2.2. Frictional properties
2.2.3. Types of cartilage damage
2.2.4. Repairs and treatment
2.2.5. Embedded Reinforcement
2.2.6. Example of an embedded solid structure
2.3. Multi layered designs
2.3.1. The construction of multilayered cartilage
2.3.2. The construction of layered osteochondral
2.3.3. Multilayered construction of homogenous scaffolds
2.4. 3D woven composite scaffolds
2.4.1. Introduction to the expansion of the scaffolds
2.4.2. Benefits of engineered fibrous scaffold architectures
2.4.3. Biomaterial fiber development for use in engineered fibrous scaffolds
2.5. Fiber and scaffold functionalization for the incorporation of stem cell homing factors
2.6. Textile cell-free scaffolds used for in situ tissue engineering
2.6.1. Knitted scaffolds
2.6.2. Woven scaffolds
2.6.3. Braided scaffolds
2.6.4. Non woven scaffolds
2.7. Clinical studies using cell free fiber based scaffolds
2.8. Electrospinning
2.8.1. Electrospinning Process
2.8.2. The technical usage of electrospinning
2.8.3. The parameters of the electrospinning
Chapter 3. Preparation and characterization of PLCL/gelatin nanafiber scaffold
3.1. Materials
3.2. The Synthesis of Poly (L-lactic acid)-co-(ε-Caprolactone)
3.3. The characteristics of poly (L-lactic acid)-co-poly(ε-caprolactone)
3.4.The electrospinning and the post treatments
3.5.The characterizations of scaffolds
3.6.The statistical analysis
3.7.Results and discussions
3.7.1. The yields of PLCL
3.7.2. The NMR results of PLCL
3.7.3. The IR results of PLCL
3.7.4. The morphology of PLCL/Gelatin scaffolds
3.7.5. The ATR-FTIR analysis of PLCL/Gelatin scaffolds
3.7.6. Mechanical properties of PLCL/gelatin scaffolds
3.7.7. The WCA of PLCL/gelatin scaffolds
Chapter 4. Conclusions from current work
参考文献
致谢
天津大学;
