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Occupational risk factors for lung cancer: A population-based case-control study in British Columbia.

机译:肺癌的职业危险因素:不列颠哥伦比亚省一项基于人群的病例对照研究。

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摘要

Occupational carcinogens have been linked to lung cancer: among 74 known occupational carcinogens and carcinogenic circumstances, 37 have been associated with lung cancer. We report on a large population-based case-control study in British Columbia (2998 lung cancer cases). In the absence of a non-cancer control group, patients with cancers other than lung cancer (11,737) served as controls. Logistic regression, adjusted for smoking history, was used to examine occupationally related lung cancer risk with histological subtypes. Elevated risk was found in several occupational circumstances: metal working, mining, deck crew of ship, bakers, workers in electric power systems, construction workers (all histological types), chefs and cooks (large cell carcinoma only), and medical workers (large cell carcinoma only). Odd ratios varied from 1.6 to 4.6, with most being around 2.0. Potential exposures found in these high risk occupational groups which warrant further evaluation include: formaldehyde, radiation, electromagnetic fields, wood dust, and cooking fumes.
机译:职业致癌物与肺癌有关:在74种已知的职业致癌物和致癌情况中,有37种与肺癌有关。我们在不列颠哥伦比亚省报告了一项基于人群的大型病例对照研究(2998例肺癌病例)。在没有非癌症对照组的情况下,以肺癌以外的癌症患者(11,737例)为对照组。根据吸烟史进行逻辑回归分析,以组织学亚型检查与职业相关的肺癌风险。在以下几种职业环境中发现了高风险:金属加工,采矿,船舶甲板工作人员,面包师,电力系统工人,建筑工人(所有组织学类型),厨师和厨师(仅适用于大细胞癌)和医务人员(仅适用于大细胞癌)仅限细胞癌)。奇数比率从1.6到4.6不等,大多数为2.0。在这些需要进一步评估的高风险职业人群中发现的潜在暴露量包括:甲醛,辐射,电磁场,木屑和烹饪油烟。

著录项

  • 作者

    Yenugadhati, Nagarajkumar.;

  • 作者单位

    University of Ottawa (Canada).;

  • 授予单位 University of Ottawa (Canada).;
  • 学科 Health Sciences Occupational Health and Safety.; Health Sciences Public Health.; Health Sciences Oncology.
  • 学位 M.Sc.
  • 年度 2007
  • 页码 235 p.
  • 总页数 235
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 职业性疾病预防;预防医学、卫生学;肿瘤学;
  • 关键词

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