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Dmca1A calcium channels regulate spontaneous calcium transients and spontaneous neurotransmitter release in Drosophila brain neurons.

机译：Dmca1A钙通道调节果蝇脑神经元中的自发钙瞬变和自发性神经递质释放。

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Calcium oscillations in the mushroom body of intact Drosophila brains are related to memory consolidation. Calcium imaging and electrophysiology are used to explore cellular and molecular mechanisms underlying calcium oscillations. Cell autonomous low-frequency spontaneous calcium transients are found in cultured mushroom body Kenyon cells and non-mushroom body neurons. PLTX-sensitive calcium channels underlie spontaneous calcium transients in the cultured neurons. A genetic approach demonstrates that the Dmca1A gene encodes PLTX-sensitive calcium channels that contribute to the spontaneous calcium transients and are also involved in spontaneous neurotransmitter release, in Drosophila brain neurons.

机译：果蝇完整大脑的蘑菇体内的钙振荡与记忆巩固有关。钙成像和电生理学用于探索钙振荡的细胞和分子机制。在培养的蘑菇体Kenyon细胞和非蘑菇体神经元中发现了细胞自主的低频自发钙瞬变。 PLTX敏感的钙通道是培养的神经元中自发钙瞬变的基础。遗传学方法表明Dmca1A基因编码果蝇脑神经元中PLTX敏感的钙通道，该通道有助于自发的钙瞬变，并且还参与自发性神经递质的释放。

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作者
Jiang, Shaojuan Amy.;
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University of California, Irvine.;

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授予单位 University of California, Irvine.;
学科 Biology Neuroscience.
学位 Ph.D.
年度 2007
页码 95 p.
总页数 95
原文格式 PDF
正文语种 eng
中图分类神经科学;
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1. Cav2-Type Calcium Channels Encoded by cac Regulate AP-Independent Neurotransmitter Release at Cholinergic Synapses in Adult Drosophila Brain. [J] . Gu H, Jiang SA, Campusano JM, Journal of Neurophysiology . 2009,第1期

机译：由cac编码的Cav2型钙通道调节成人果蝇大脑中胆碱能突触的AP独立神经递质释放。
2. Large conductance calcium-activated potassium channels affect both spontaneous firing and intracellular calcium concentration in cerebellar Purkinje neurons. [J] . Womack MD, Hoang C, Khodakhah K Neuroscience: An International Journal under the Editorial Direction of IBRO . 2009,第4期

机译：大电导的钙激活钾通道会影响小脑浦肯野神经元的自发放电和细胞内钙浓度。
3. Ca_v3--type alpha1T calcium channels mediate transient calcium currents that regulate repetitive firing in Drosophila antennal lobe PNs [J] . Jorge Iniguez, Soleil S. Schutte, Diane K. ODowd Journal of Neurophysiology . 2013,第4期

机译：Ca_v3型alpha1T钙通道介导调节果蝇触角PN中重复发射的瞬时钙电流
4. Calcium beat: internal calcium stores regulating the rhythm of spontaneous neurotransmitter release [C] . Leao, R.N., Oleskevich, . 2002

机译：钙搏动：内部钙存储调节自发性神经递质释放的节奏
5. Mechanism for spontaneous calcium activity and spinal cord neurotransmitter specification, and the role of calcium activity in dopamine specification in the brain and spinal cord. [D] . Velazquez Ulloa, Norma Andrea. 2009

机译：自发钙活性和脊髓神经递质指标的机制，以及钙活性在脑和脊髓中多巴胺指标中的作用。
6. Cav2-Type Calcium Channels Encoded by cac Regulate AP-Independent Neurotransmitter Release at Cholinergic Synapses in Adult Drosophila Brain [O] . Huaiyu Gu, Shaojuan Amy Jiang, Jorge M. Campusano, -1

机译：由cac编码的Cav2型钙通道调节成人果蝇脑中胆碱能突触的AP独立神经递质的释放。
7. Cav2-Type Calcium Channels Encoded by cac Regulate AP-Independent Neurotransmitter Release at Cholinergic Synapses in Adult Drosophila Brain [O] . Gu, Huaiyu, Jiang, Shaojuan Amy, Campusano, Jorge M., 2008

机译：由cac编码的Cav2型钙通道调节成人果蝇脑中胆碱能突触的AP独立神经递质的释放。

Dmca1A calcium channels regulate spontaneous calcium transients and spontaneous neurotransmitter release in Drosophila brain neurons.

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