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首页> 外文学位 >Cost Utility Analysis of Balloon Kyphoplasty and Vertebroplasty in the Treatment of Vertebral Compression Fractures in the United States.
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Cost Utility Analysis of Balloon Kyphoplasty and Vertebroplasty in the Treatment of Vertebral Compression Fractures in the United States.

机译：在美国，治疗椎体压缩性骨折的球囊后凸成形术和椎体成形术的成本效用分析。

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摘要

Vertebral compression fractures are associated with chronic pain, decreased health related quality of life and high health care costs. Balloon kyphoplasty and vertebroplasty are vertebral augmentation procedures, widely used by spine surgeons to relieve pain in these patients. A number of studies have been conducted to compare and contrast the effectiveness of both these techniques and have reported that balloon kyphoplasty offers a long lasting pain relief compared to vertebroplasty. However, kyphoplasty procedure is also more expensive than vertebroplasty. With the limited resources and the need of justification of patient selection, it is important to address whether the additional benefits offered by kyphoplasty are worth the additional costs. We performed a cost utility analysis from a payer's perspective using a Markov model to assess the cost utility of balloon kyphoplasty compared to vertebroplasty. Health utility data was obtained from previously conducted clinical trials. Direct medical cost associated with each of these procedures were obtained through an observational study conducted from the payer's perspective. Sensitivity analysis was performed to assess the robustness of the results around uncertainties in cost and utility parameters. The incremental cost utility of balloon kyphoplasty was
机译：椎骨压缩性骨折伴有慢性疼痛，与健康有关的生活质量下降和较高的医疗保健费用。球囊后凸成形术和椎体成形术是椎体隆突手术，脊柱外科医生广泛用于减轻这些患者的疼痛。已经进行了许多研究来比较和对比这两种技术的有效性，并且已经报道，与椎体成形术相比，球囊后凸成形术可提供长期的疼痛缓解。但是，后凸成形术也比椎骨成形术昂贵。由于资源有限且需要合理选择患者，因此必须解决椎体后凸成形术提供的其他好处是否值得额外费用的问题。我们使用马尔可夫模型从付款人的角度进行了成本效用分析，以评估与椎体成形术相比，球囊后凸成形术的成本效用。从以前进行的临床试验中获得卫生实用数据。通过从付款人的角度进行的一项观察性研究，可以获得与这些程序相关的直接医疗费用。进行了敏感性分析，以评估围绕成本和效用参数不确定性得出的结果的稳健性。球囊后凸成形术的增量成本效用为

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  • 作者

    Borse, Mrudula.;

  • 作者单位

    The University of Toledo.;

  • 授予单位 The University of Toledo.;
  • 学科 Health Sciences Pharmacy.;Health Sciences Medicine and Surgery.
  • 学位 M.S.P.S.
  • 年度 2013
  • 页码 74 p.
  • 总页数 74
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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