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The influence of waiting time on treatment choices among prostate cancer patients.

机译:等待时间对前列腺癌患者治疗选择的影响。

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摘要

Objectives. (1) To examine the spatial and temporal patterns in the length of time patients waited for treatment for prostate cancer from 1996 to 2001 in Ontario. (2) To evaluate the influence of recent treatment waiting times, at the time a patient was diagnosed with prostate cancer, on the type of treatment selected.;Results. 24% of the study population selected radiotherapy as the curative treatment option and 48% selected surgery as the curative treatment option. Median waiting times were 148 and 91 days respectively. Differences in median (actual) waiting time for radiotherapy or surgery treatment of greater than 2 weeks were observed according to CCO treatment region and calendar year.;The prevailing waiting times for radiotherapy and for surgery were not related to the choice of any treatment (radiotherapy or surgery) versus no treatment, nor related to the choice of radiotherapy versus surgery. Among the covariates investigated, decreasing age, higher SES of residence county, more recent year, and specific CCO regions were associated with the selection of any treatment versus no treatment. Increasing age, further distance to a comprehensive cancer centre, and specific CCO regions were associated with selection of radiotherapy versus surgery. Patients with a higher socio-economic residence area and diagnosis at a prostatectomy centre were more likely to have surgery than radiotherapy.;Conclusion The prevailing waiting time at diagnosis did not influence treatment choices among patients with localized prostate cancer.;Methods. A retrospective cohort study was conducted on 17,626 prostate cancer patients diagnosed between 1996 and 2001 in Ontario. To address the first objective, the individual waiting time was defined as the interval from the date of diagnosis to the start of the initial treatment. The spatial and temporal patterns of interest were investigated. To address the second objective, the exposure of interest was defined as the prevailing waiting time for radiotherapy and surgery in the 3 months prior to diagnosis. The individual prevailing waiting time assignment was dependent on a patient's county of residence and the calendar month and year at diagnosis. Separate logistic regression models were established to examine the effect of prevailing waiting time on treatment selected---curative treatment (radiotherapy/surgery) versus neither treatment, and radiotherapy versus surgery, after controlling other covariates.
机译:目标。 (1)研究1996年至2001年安大略省患者等待前列腺癌治疗的时间长度的时空格局。 (2)在患者被诊断出患有前列腺癌时,评估最近的治疗等待时间对所选治疗类型的影响。 24%的研究人群选择放射疗法作为治疗选择,48%的选择手术作为治疗选择。中位轮候时间分别为148天及91天。根据CCO治疗区域和日历年,观察到放疗或手术治疗的中位(实际)等待时间大于2周的差异。;放疗和手术的主要等待时间与任何治疗的选择无关(放疗)或手术)与不进行治疗,也与放疗与手术的选择无关。在所调查的协变量中,年龄的降低,居住县的SES较高,最近的年份以及特定的CCO地区与选择任何治疗与未治疗的选择有关。年龄的增加,距综合癌症中心的距离以及特定的CCO区域与放疗与手术的选择有关。具有较高社会经济居住区并在前列腺切除术中心进行诊断的患者比放疗更有可能进行手术。结论结论确诊的主要等待时间不影响局部前列腺癌患者的治疗选择。回顾性队列研究对1996年至2001年在安大略省诊断出的17,626例前列腺癌患者进行了研究。为了实现第一个目标,将个人等待时间定义为从诊断日期到开始治疗的间隔时间。研究了感兴趣的时空格局。为了实现第二个目标,将感兴趣的照射定义为诊断前3个月中放疗和手术的主要等待时间。各个患者的主要等待时间分配取决于患者的居住县和诊断时的日历年月。建立了独立的逻辑回归模型,以检查在选择其他协变量后,主要等待时间对所选治疗的影响-根治性治疗(放疗/手术)与既不治疗,以及放疗与手术。

著录项

  • 作者

    Huang, Miaojing.;

  • 作者单位

    Queen's University (Canada).;

  • 授予单位 Queen's University (Canada).;
  • 学科 Public health.;Oncology.
  • 学位 M.Sc.
  • 年度 2006
  • 页码 121 p.
  • 总页数 121
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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