• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Well-defined functional polymers: Synthesis by living polymerizations, functional group modifications, and structural transformations to robust nanoobjects.
【24h】

Well-defined functional polymers: Synthesis by living polymerizations, functional group modifications, and structural transformations to robust nanoobjects.

机译：定义明确的功能聚合物：通过活性聚合，官能团修饰和结构转变为坚固的纳米物体进行合成。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This dissertation focuses on the development of synthetic methodologies for the preparation of well-defined macromolecules with various architectures, diverse functionalities, abilities to transform into nanostructures, as well as potential biomedical applications. A variety of functional polymers such as poly(1-alkene-co-maleic anhydride) alternating copolymers, alkenyl-functionalized polymers, pyrrolidinone-functionalized fluoropolymers, hyperbranched iodine-containing polymers, star block copolymers and amphiphilic core-shell brush copolymers were synthesized by using living polymerization techniques, including reversible addition-fragmentation chain transfer radical (RAFT) polymerization, atom transfer radical polymerization (ATRP) and ring-opening metathesis polymerization (ROMP) or their combinations. High degree control of polymer molecular weights, topologies and functionalities were achieved based on the synthetic strategies described in this dissertation. The structure-property relationships of these macromolecules were investigated by using a number of characterization methods. Structural transformations of these functional polymers into micelle assemblies, star polymer nanoparticles and amphiphilic cross-linked networks with nanoscale features were demonstrated, and these nanostructures were further studied by microscopic techniques. These functional polymers may have interesting applications in nanomedicine. For example, the hyperbranched iodopolymers and well-defined aqueous iodinated nanoparticles synthesized were investigated as new X-ray contrast media for computed tomography imaging.
机译：本论文着重于合成方法的发展，以制备具有多种结构，多种功能，转化为纳米结构的能力以及潜在的生物医学应用的定义明确的大分子。合成了多种功能聚合物，例如聚（1-烯烃-马来酸酐共聚物）交替共聚物，烯基官能化的聚合物，吡咯烷酮官能化的含氟聚合物，含碘超支化的聚合物，星形嵌段共聚物和两亲性的核-壳刷共聚物。使用活性聚合技术，包括可逆加成-断裂链转移自由基聚合（RAFT）聚合，原子转移自由基聚合（ATRP）和开环易位聚合（ROMP）或它们的组合。基于本文描述的合成策略，实现了对聚合物分子量，拓扑结构和功能性的高度控制。通过使用多种表征方法研究了这些大分子的结构-性质关系。这些功能性聚合物的结构转变为胶束组装体，星形聚合物纳米颗粒和具有纳米级特征的两亲性交联网络，并通过显微镜技术进一步研究了这些纳米结构。这些功能聚合物可能在纳米医学中具有有趣的应用。例如，研究了合成的超支化碘聚合物和定义明确的水性碘代纳米颗粒，作为用于计算机断层扫描成像的新型X射线造影剂。

著录项

  • 作者

    Ma, Jun.;

  • 作者单位

    Washington University in St. Louis.;

  • 授予单位 Washington University in St. Louis.;
  • 学科 Chemistry Organic.;Chemistry Polymer.
  • 学位 Ph.D.
  • 年度 2010
  • 页码 275 p.
  • 总页数 275
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号