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Prevalence of anemia, poor trace element status, and factors associated with anemia and poor trace element status among children 12--36 months of age from low-income families.

机译:低收入家庭12--36个月大的儿童中贫血患病率,微量元素状况不佳以及与贫血和微量元素状况有关的因素。

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摘要

Prevalences of anemia, low iron stores, iron deficiency (ID), iron deficiency anemia (IDA), and marginal zinc status were determined in a cross-sectional study of children 12--36 months of age participating in the Supplemental Nutrition Program for Women, Infants and Children (WIC) in two California counties. Additional objectives were to assess the value of using hemoglobin to predict ID, and to determine factors associated with anemia, ID, serum zinc and copper.; The prevalence of anemia was 11.1% (hemoglobin 110 g/L at 12--24 mo, 111 g/L at 24--36 mo). Hemoglobin was regressed on ferritin, transferrin receptors, and transferrin saturation to determine abnormal values (study-determined), using a two phase segmented linear regression model. Study- or literature-determined abnormal values were: serum ferritin ≤8.7 or 10.0 mug/L, serum transferrin receptor ≥8.4 or >10.0 mug/mL, and transferrin saturation ≤13.2% or 10.0%, respectively. The prevalence of low iron stores (ferritin) was 24.8% or 29.0%, ID (≥2 abnormal iron measures) was 16.2% or 8.8%, and IDA (ID with low hemoglobin) was 3.4% or 3.2% using study-or literature-determined cut-offs, respectively. Hemoglobin concentration was used to predict study- and literature-determined ID using receiver operator characteristic (ROC) curves. The sensitivity of low hemoglobin in predicting study- and literature-determined ID was low (23.2% and 40.0%, respectively).; Children currently participating in WIC, and maternal WIC participation during pregnancy were protective against anemia and ID, respectively. Children with a greater rate of weight gain were less likely, and children of pregnant mothers were more likely to be anemic. Males, children living in an urban location, children of pregnant mothers, and children consuming 125 ml/day of orange/tomato juice were more likely to be ID.; The prevalence of low serum zinc (10.7 muM) was 42.8%. Consumption of sweetened beverages and maternal pica during pregnancy were negatively, and consumption of >15 g/day of meat was positively associated with serum zinc. Prevalence of low serum copper (14.2 muM) was 1%. Mean serum copper was 23.6 (+/-3.5) and 22.1 (+/-3.8) muM for anemic and non-anemic children, respectively (t-test, P = 0.026). Factors positively associated with serum copper were current consumption of breastmilk and consumption of >15 g/day of beans.
机译:在一项针对参加妇女补充营养计划的12--36个月大的儿童的横断面研究中确定了贫血,铁缺乏症,铁缺乏症(ID),铁缺乏症贫血(IDA)和边缘锌状态的患病率,加利福尼亚两个县的婴儿和儿童(WIC)。其他目标是评估使用血红蛋白预测ID的价值,并确定与贫血,ID,血清锌和铜有关的因素。贫血的患病率为11.1%(血红蛋白在12--24 mo时<110 g / L,在24--36 mo时<111 g / L)。使用两阶段分段线性回归模型,对铁蛋白,转铁蛋白受体和转铁蛋白饱和度进行血红蛋白回归以确定异常值(由研究确定)。研究或文献确定的异常值为:血清铁蛋白≤8.7或<10.0杯/升,血清转铁蛋白受体≥8.4或> 10.0杯/毫升,转铁蛋白饱和度分别≤13.2%或<10.0%。根据研究或文献,低铁存储(铁蛋白)的患病率为24.8%或29.0%,ID(≥2种异常铁测量)的患病率为16.2%或8.8%,IDA(低血红蛋白的ID为3.4%或3.2%)确定的临界值。血红蛋白浓度用于通过接收者操作者特征曲线(ROC)预测研究和文献确定的ID。低血红蛋白对预测研究和文献确定的ID的敏感性较低(分别为23.2%和40.0%)。当前参加WIC的儿童和孕妇在怀孕期间参加WIC分别可预防贫血和ID。体重增加率较高的孩子患贫血的可能性较小,怀孕母亲的孩子贫血的可能性较大。男性,居住在城市的儿童,怀孕的母亲的儿童以及每天摄入少于125毫升橙汁/番茄汁的儿童更容易成为ID。低血清锌(<10.7μM)的患病率为42.8%。怀孕期间甜味饮料和母性异食癖的摄入量为负,而每天摄入> 15克肉与血清锌呈正相关。低血清铜(<14.2μM)的患病率<1%。贫血和非贫血儿童的平均血清铜分别为23.6(+/- 3.5)和22.1(+/- 3.8)μM(t检验,P = 0.026)。与血清铜呈正相关的因素是母乳的当前消耗量和豆> 15 g /天的消耗量。

著录项

  • 作者

    Schneider, Julie Michele.;

  • 作者单位

    University of California, Davis.;

  • 授予单位 University of California, Davis.;
  • 学科 Health Sciences Nutrition.
  • 学位 Ph.D.
  • 年度 2005
  • 页码 128 p.
  • 总页数 128
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 预防医学、卫生学;
  • 关键词

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