• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Vitamin B-12 deficiency in Guatemalan mothers and infants: Prevalence, predictors and associations with maternal depression and infant development.
【24h】

Vitamin B-12 deficiency in Guatemalan mothers and infants: Prevalence, predictors and associations with maternal depression and infant development.

机译：危地马拉母亲和婴儿的维生素B-12缺乏症：患病率，预测因素以及与母亲抑郁和婴儿发育的关联。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The objective of this research was to determine the prevalence of deficient plasma vitamin B-12 concentrations in Guatemalan infants and their mothers, and evaluate associations with deficiency. Subjects were 304 Guatemalan infants, 80% of whom were breastfeeding, and their mothers. Exclusion criteria for infants included twins, severe stunting or wasting, reported health problems, severe developmental delay, hemoglobin (Hb) 95 g/L, maternal age 17 y, and maternal pregnancy >3 mo. Socio-economic status and home environment (HOME) data were collected. Infant and maternal anthropometric measures were performed. Vitamin B-12 intake from complementary foods was estimated with a food frequency questionnaire (FFQ), and breastfeeding frequency was reported by mothers. A complete blood count (CBC), and plasma vitamin B-12, folate, ferritin, and C-reactive protein (CRP) were measured. Maternal depressive symptoms were evaluated using the Center for Epidemiological Studies-Depression (CES-D) scale. The Bayley Scale II Mental, Motor, and Behavioral Rating Scales (BSR), the Preschool Language Scale (PLS), and the Temperament and Atypical Behavior Scale (TABS) were used to assess infant developmental status. Deficient and marginal plasma vitamin B-12 concentrations were found in 29.8% and 19.5% of infants, and 35.7% and 32.5% of mothers, respectively. Anemia was present in 14.5% of infants and 9.8% of mothers. Daily vitamin B-12 intake averaged 3.6 ug in mothers and 2.4 ug from complementary foods in infants. In linear regression analysis, higher maternal plasma vitamin B-12, higher B-12 intake from complementary foods, lower frequency of breastfeeding, and larger household size predicted infant plasma vitamin B-12 concentrations (P 0.0001). A CES-D score ≥16 was found in 43% of women, and these women had, on average, more children (P 0.05), a higher BMI (P 0.05), a lower platelet count (P 0.05), and a lower plasma vitamin B-12 concentration (P 0.005) than women with less symptoms. Infants with deficient plasma vitamin B-12 concentrations had poorer performance of motor skills related to secure walking compared to adequate infants (P 0.005), and those consuming 1.44 ug/d of vitamin B-12 from complementary foods had a lower mean MDI score than infants consuming >1.44 ug/d (P 0.05). Additional studies and supplementation trials are needed to confirm these associations.
机译：这项研究的目的是确定危地马拉婴儿及其母亲的血浆维生素B-12缺乏症的患病率，并评估与缺乏症的关联。受试者为304名危地马拉婴儿及其母亲，其中80％为母乳喂养。婴儿的排除标准包括双胞胎，严重发育不良或消瘦，已报告的健康问题，严重的发育迟缓，血红蛋白（Hb）<95 g / L，产妇年龄<17岁和产妇怀孕> 3 mo。收集了社会经济状况和家庭环境（HOME）数据。进行了婴幼儿人体测量。通过食物频率调查表（FFQ）估算了辅食中维生素B-12的摄入量，母亲报告了母乳喂养的频率。测量全血细胞计数（CBC），血浆维生素B-12，叶酸，铁蛋白和C反应蛋白（CRP）。产妇抑郁症状的评估使用了流行病学研究中心的抑郁症（CES-D）量表。使用Bayley量表II的心理，运动和行为评定量表（BSR），学龄前语言量表（PLS）以及气质和非典型行为量表（TABS）评估婴儿的发育状况。分别有29.8％和19.5％的婴儿以及35.7％和32.5％的母亲发现血浆维生素B-12的浓度不足和微不足道。贫血发生在14.5％的婴儿和9.8％的母亲中。母亲平均每日摄取维生素B-12的量为3.6 ug，婴儿补充食物平均为2.4 ug。在线性回归分析中，孕妇血浆维生素B-12含量较高，辅食摄入的维生素B-12含量较高，母乳喂养的频率较低以及家庭规模较大，都可以预测婴儿血浆维生素B-12的浓度（P <0.0001）。在43％的女性中发现CES-D得分≥16，这些女性平均有更多的孩子（P <0.05），BMI较高（P <0.05），血小板计数较低（P <0.05），与症状较少的女性相比，血浆维生素B-12浓度较低（P <0.005）。与足够的婴儿相比，血浆维生素B-12浓度不足的婴儿与安全步行有关的运动技能表现较差（P <0.005），而从辅食中摄入的维生素B-12含量低于1.44 ug / d的婴儿的平均MDI较低得分高于食用> 1.44 ug / d的婴儿（P <0.05）。需要其他研究和补充试验以确认这些关联。

著录项

  • 作者

    Jones, Katharine Mary.;

  • 作者单位

    University of California, Davis.;

  • 授予单位 University of California, Davis.;
  • 学科 Health Sciences Nutrition.
  • 学位 Ph.D.
  • 年度 2005
  • 页码 169 p.
  • 总页数 169
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 预防医学、卫生学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号