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首页> 外文学位 >Evaluating the severity of acute respiratory infections: Advantage of meditation over exercise; Viral and bacterial co-infection; and Reduction of Wisconsin Upper Respiratory Symptom Survey.
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Evaluating the severity of acute respiratory infections: Advantage of meditation over exercise; Viral and bacterial co-infection; and Reduction of Wisconsin Upper Respiratory Symptom Survey.

机译：评估急性呼吸道感染的严重程度：冥想胜于运动；病毒和细菌共同感染；和减少威斯康星州上呼吸道症状调查。

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摘要

Acute respiratory infection (ARI) exerts a heavy financial burden on the US health care system and afflicts persons of all ages. Using the Wisconsin Upper Respiratory Symptom Survey (WURSS), a study on "Meditation or Exercise for Preventing Acute Respiratory Infection" (MEPARI) showed trainings in meditation or exercise can reduce illness outcomes compared to control, however, meditation fostered better reduction of global severity of illness than exercise. This thesis expands on this finding by evaluating the advantage of meditation over exercise and identifying specific WURSS items responsible for the difference. This work also broadens research on severity of ARI illness by evaluating frequency of bacterial co-infection and also demonstrating a shorter version of the WURSS used in assessing ARI unwellness.;Using data from n=149 adults who completed the MEPARI trial between 2009 and 2010, this dissertation showed meditators had improved quality of life compared to exercisers. Compared to WURSS items representing specific symptoms, items symbolizing function and quality of life were responsible for greater reduction in global severity of illness. Using data from n=194 randomly selected nasal wash specimens which were obtained from participants with ARI illness between 2004 and 2008, this thesis showed presence of pathogenic bacteria may be associated with increased inflammatory biomarkers. Compared to virus-positive illness, virus-negative illness may be associated with more pathogenic bacteria. Finally, this work combined WURSS-21 data from 4 separate trials including MEPARI and demonstrated a shorter and reliable WURSS-11 using factor analysis. This new WURSS-11 showed similar dimensional structure as the older WURSS-21.;The results of this dissertation have significant public health implications. They support the use of meditation or exercise which may help reduce the burden of ARI illness. It also extends scientific knowledge on bacterial association during illness. Future research is not only needed to validate the WURSS-11 but to evaluate the frequency of nasal pathogenic bacteria in asymptomatic adults.
机译：急性呼吸道感染（ARI）给美国医疗保健系统带来沉重的经济负担，并困扰着各个年龄段的人。使用威斯康星州上呼吸道症状调查（WURSS），一项有关“冥想或运动以预防急性呼吸道感染”（MEPARI）的研究表明，与控制相比，冥想或运动训练可以减少疾病的发生，但是，冥想可以更好地减轻全球严重程度疾病胜于运动。本文通过评估冥想优于运动的优势并确定造成这种差异的具体WURSS项目来扩展这一发现。这项工作还通过评估细菌共感染的频率，并展示了用于评估ARI不适的WURSS的较短版本，扩大了ARI疾病严重程度的研究。;使用了2009年至2010年间完成MEPARI试验的n = 149名成年人的数据，该论文表明，与锻炼者相比，冥想者的生活质量得到了改善。与代表特定症状的WURSS项目相比，象征功能和生活质量的项目可更大程度地降低全球疾病的严重程度。利用从2004年至2008年间从ARI疾病参与者中随机抽取的194份鼻洗样本的数据，本论文表明病原细菌的存在可能与炎性生物标志物的增加有关。与病毒阳性疾病相比，病毒阴性疾病可能与更多的致病细菌有关。最后，这项工作结合了包括MEPARI在内的4个不同试验的WURSS-21数据，并使用因子分析证明了更短且可靠的WURSS-11。这种新的WURSS-11的尺寸结构与旧的WURSS-21相似。他们支持冥想或运动，可以帮助减轻ARI疾病的负担。它还扩展了疾病期间细菌缔合的科学知识。不仅需要进一步的研究来验证WURSS-11，而且需要评估无症状成人中鼻病原菌的发生频率。

著录项

  • 作者

    Obasi, Chidi N.;

  • 作者单位

    The University of Wisconsin - Madison.;

  • 授予单位 The University of Wisconsin - Madison.;
  • 学科 Medicine.;Public health.;Epidemiology.
  • 学位 Ph.D.
  • 年度 2012
  • 页码 93 p.
  • 总页数 93
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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