首页> 外文学位 >Finite-difference time-domain modeling of a waveguide-based radio frequency exposure system for studying nonthermal effects on catecholamine release from chromaffin cells: Characterization and optimization.
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Finite-difference time-domain modeling of a waveguide-based radio frequency exposure system for studying nonthermal effects on catecholamine release from chromaffin cells: Characterization and optimization.

机译:基于波导的射频暴露系统的有限差分时域建模,用于研究对嗜铬细胞释放儿茶酚胺的非热效应:表征和优化。

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摘要

The scope of this thesis is two-fold. (1) To optimize the waveguide exposure system incorporating a cell perfusion apparatus (CPA) so as to provide maximum homogeneity of the electromagnetic fields (EMF) and specific absorption rate (SAR) in the region containing the biological cells. (2) To provide a detailed characterization of the EMF and SAR at the location of the cells. These two goals were achieved via numerical FDTD modeling. Macroscopic modeling was performed where the minimum Yee cell size used in the FDTD model was a fraction of a millimeter, representing accurately the waveguide and CPA physical structures. Preliminary microscopic modeling was also accomplished where the minimum Yee cell size was on the order of 0.1 mum, making it possible to take into account the basic morphological features of bovine adrenal medullar chromaffin cells used in the RF/MW exposure experiments. (Abstract shortened by UMI.).
机译:本论文的范围有两个方面。 (1)优化包含细胞灌注设备(CPA)的波导曝光系统,以在包含生物细胞的区域中提供最大的电磁场(EMF)和比吸收率(SAR)均匀性。 (2)提供细胞位置处的EMF和SAR的详细表征。这两个目标是通过数字FDTD建模实现的。进行宏观建模,其中FDTD模型中使用的最小Yee像元大小为毫米的几分之一,准确地表示了波导和CPA的物理结构。还完成了初步显微建模,其中最小Yee细胞大小约为0.1微米,从而有可能考虑到RF / MW暴露实验中使用的牛肾上腺髓质嗜铬细胞的基本形态特征。 (摘要由UMI缩短。)。

著录项

  • 作者

    Hagan, Todd.;

  • 作者单位

    University of Nevada, Reno.;

  • 授予单位 University of Nevada, Reno.;
  • 学科 Electrical engineering.
  • 学位 M.S.
  • 年度 2005
  • 页码 140 p.
  • 总页数 140
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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