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Longitudinal outcomes of distortion product otoacoustic emissions and wideband reflectance in infants.

机译:婴儿畸变产物耳声发射和宽带反射率的纵向结果。

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摘要

Clinical practice has shown that some infants are born with, or develop a temporary conductive hearing loss characterized by the absence of measurable otoacoustic emissions (OAEs) but normal sensorineural hearing. This transient situation interferes with the process of universal newborn hearing screening and identification.;The purpose of this prospective, longitudinal study was to describe outcomes of distortion product OAE (DPOAE) screening in infants at birth, and one, four, eight, and twelve weeks of age. In addition, wideband reflectance (WBR) measures, which have the potential to help characterize outer-ear canal and middle-ear function, were examined to determine their potential utility in identifying DPOAE screening outcomes.;Beginning with a sample of 50% of ears that passed the initial DPOAE screening at birth, results showed that passing outcomes rose over the course of time, at rates of 72.1%, 84.6%, 86.0%, and 96.0% at weeks one, four, eight, and twelve, respectively. Rates of new fails - ears that had passed the screening at a previous time point - also increased over time, with the exception of the last time point, at which no new failing outcomes were seen. These data suggest that twelve weeks would be the most efficient time for re-evaluation of infants, and that four weeks would be an appropriate alternative.;Confidence intervals of reflectance measures were calculated for DPOAE outcomes at each time point. Reflectance outcomes were distributed such that fail and pass DPOAE outcomes could be predicted from the highest and lowest values, with an area of ambiguity in between. Receiver operating characteristic curves were calculated to determine the reflectance frequencies that would provide the highest predictive value at each time point. In addition, this method was used to determine how well WBR could be used to predict DPOAE outcomes at future time points. The predictive value of WBR for future DPOAE outcomes was poorer than concurrent prediction and likely has little clinical utility at present. However, low WBR values in the face DPOAE screening failures should cause concern for sensorineural hearing loss and can be used to prioritize such infants for follow-up audiologic evaluation.
机译:临床实践表明,某些婴儿出生时或患有暂时性传导性听力损失,其特征是缺乏可测量的耳声发射(OAE),但感觉神经听力正常。这种短暂的情况会干扰新生儿通用听力筛查和鉴定的过程。这项前瞻性纵向研究的目的是描述婴儿出生时畸变产物OAE(DPOAE)筛查的结果,以及一,四,八和十二岁婴儿的筛查结果。周龄。此外,还对宽带反射率(WBR)措施(可能有助于表征外耳道和中耳功能)进行了检查,以确定它们在识别DPOAE筛查结果中的潜在效用。从50%的耳朵开始在出生时通过最初的DPOAE筛查的结果表明,通过结局的结果随着时间的流逝而上升,在第1、4、8和12周分别达到72.1%,84.6%,86.0%和96.0%。新的失败率(在上一个时间点通过筛查的耳朵)也随着时间的推移而增加,但最后一个时间点除外,在该时间点未发现新的失败结果。这些数据表明,十二周将是重新评估婴儿的最有效时间,而四周将是一个合适的替代方法。;在每个时间点计算DPOAE结果的反射率置信区间。分布反射结果,以便可以通过最高值和最低值来预测失败和通过DPOAE的结果,并且介于两者之间。计算接收器工作特性曲线以确定在每个时间点将提供最高预测值的反射率频率。此外,该方法还用于确定WBR在将来的时间点可以用来预测DPOAE结果的程度。 WBR对未来DPOAE结局的预测价值比并发预测差,目前可能几乎没有临床用途。然而,在面部DPOAE筛查失败时,较低的WBR值应引起对感音神经性听力损失的关注,并可用于对此类婴儿进行优先级的后续听力学评估。

著录项

  • 作者

    Ramachandran, Virginia.;

  • 作者单位

    Wayne State University.;

  • 授予单位 Wayne State University.;
  • 学科 Audiology.
  • 学位 Ph.D.
  • 年度 2012
  • 页码 90 p.
  • 总页数 90
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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