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An exploration of the living and working environments of esophageal cancer patients: Gaining a contextual understanding of the risk factors for disease.

机译：食管癌患者生活和工作环境的探索：对疾病危险因素的背景了解。

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摘要

Introduction: The etiology of esophageal cancer is mainly studied using traditional epidemiological research approaches. Although these approaches have led to insight on the risk factors of disease, findings reported in studies utilizing such conventional approaches often peel away the context surrounding these risk factors.;Methods: A narrative research design was applied which utilized the lifegrid alongside a semi-structured interview guide, occupational and residential summary boxes, occupational risk maps and residential pictures, and a series of other supplementary research tools. A sample of forty-six esophageal cancer patients drawn from participating Toronto and London Ontario hospitals shared their life stories as they pertained to key etiological factors. Emphasis was placed on the latency period. Data was analyzed using holistic-content, categorical-content, and chi-square analyses.;Results: The unconventional use of a nested approach considered the different levels of risk factors for esophageal cancer. This elucidated the social and environmental dimensions at play demonstrating how risk factors for EC are sandwiched between individual resources and macro environmental forces. As such, lived experiences and exposures do not occur in isolation. The lifegrid was administered for the first time as an analytical tool to conduct holistic-content analysis. These results, alongside those generated via various other forms of analyses, validated current knowledge and allowed for a context-sensitive understanding of the risk factors for esophageal cancer which considered both timing and place.;Conclusions: By examining both the living and working environments of esophageal cancer patients in this unconventional way, a context-sensitive understanding of the inter-related and deeper-rooted causes of this disease were provided. This study demonstrated how the adoption of alternative research approaches can and should be utilized in order to gain better insight to the etiology of disease. The findings of this research can aid in providing a clearer understanding of the risk factors of disease so that more targeted prevention and intervention strategies and policies can be developed.;Objectives: The main objective of this study was to gain a context-sensitive understanding of the risk factors for esophageal cancer by examining the living and working environments of these patients through the use of a less conventional research approach.
机译：简介：食管癌的病因主要是采用传统的流行病学研究方法进行研究。尽管这些方法已经使人们对疾病的危险因素有了更深入的了解，但使用这种常规方法进行的研究报告中的发现常常剥夺了围绕这些危险因素的背景。方法：采用叙述性研究设计，该方法利用救生网和半结构化结构面试指南，职业和住宅摘要框，职业风险图和住宅图片，以及一系列其他补充研究工具。从参加活动的多伦多和安大略省伦敦的医院抽取的46例食道癌患者的样本分享了他们的生活经历，因为它们与关键病因有关。重点放在潜伏期。使用整体内容，类别内容和卡方分析来分析数据。结果：嵌套方法的非常规使用考虑了食管癌危险因素的不同水平。这阐明了正在发挥作用的社会和环境层面，证明了欧共体的风险因素是如何夹在单个资源和宏观环境力量之间的。因此，生活经历和接触并不是孤立发生的。救生网首次作为进行整体内容分析的分析工具进行管理。这些结果与通过其他各种形式的分析得出的结果一起，验证了当前的知识，并允许对食道癌危险因素进行上下文敏感的理解，同时考虑了时机和地点。结论：通过检查食管癌患者的生活和工作环境食道癌患者以这种非常规的方式，对这种疾病的相互关联和更深层次的原因提供了上下文相关的理解。这项研究证明了如何可以采用替代研究方法，以更好地了解疾病的病因。这项研究的结果可以帮助人们更清楚地了解疾病的危险因素，从而可以制定更有针对性的预防和干预策略和政策。目的：本研究的主要目的是获得对环境的敏感性通过使用不太传统的研究方法来检查这些患者的生活和工作环境，从而确定食道癌的危险因素。

著录项

  • 作者

    Novogradec, Ann.;

  • 作者单位

    York University (Canada).;

  • 授予单位 York University (Canada).;
  • 学科 Health Sciences Epidemiology.;Health Sciences Oncology.;Health Sciences Public Health.
  • 学位 Ph.D.
  • 年度 2012
  • 页码 550 p.
  • 总页数 550
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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