• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Arsenic in community drinking water systems and small for gestational age birth, pregnancy-related hypertension, and stillbirth in Utah, 1989--2006.
【24h】

Arsenic in community drinking water systems and small for gestational age birth, pregnancy-related hypertension, and stillbirth in Utah, 1989--2006.

机译：1989--2006年，犹他州社区饮用水系统中的砷，以及胎龄，妊娠相关的高血压和死胎中的砷。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The purpose of this dissertation research was to investigate whether there is an association between exposure to low to moderate levels of arsenic in drinking water in community water systems (CWSs) and small for gestational age birth (SGA), pregnancy-related hypertension, and/or stillbirth. The study included over 633,000 live births and stillbirths to Utah residents during 1989 to 2006 where the maternal addresses recorded on birth and fetal death certificates were within the boundaries of a CWS. Over 97% of the maternal addresses in each county were geocoded and then spatially linked to georeferenced data layers of 476 CWS service areas statewide and to elevation data. Water quality data collected for regulatory purposes were used to estimate annual average arsenic levels for each CWS; these values were assigned to the births and stillbirths based on the first trimester of the year of pregnancy and the CWS providing water to the maternal residence. Arsenic levels were less than 2.5 micrograms per liter (mug/L) for the majority of residences (73.8%); arsenic levels were greater than 10 ig/L at only 3.7% of the residences. There was a small but statistically significant association between arsenic concentration and SGA. Using 2.5 mug/L as the reference, the adjusted odds ratio (aOR) for SGA was 1.04, (95% confidence interval (CI) 1.00, 1.07) when arsenic levels were 5.1 to 9.9 mug/L (p-value 0.03), and aOR 1.07 (CI 1.03, 1.12) when levels were 10 mug/L or greater (p-value 0.002). At arsenic levels from 2.5 to 5 mug/L, there was a small, but not statistically significant (p-value 0.40), increase in SGA (aOR 1.01, CI 0.98, 1.04). Arsenic was not found to be associated with pregnancy-related hypertension, nor was there an association between low to moderate levels of arsenic in drinking water and stillbirth. An additional finding was that, compared with births at elevations less than 3,000 feet(ft), the frequency of SGA increased with every 1,000 ft increase in elevation to an aOR of 1.91 (CI 1.65, 2.22) for women residing above 6,000 ft.
机译：本研究的目的是调查在社区供水系统（CWS）中饮用水中低至中等水平的砷暴露与胎龄儿（SGA），妊娠相关的高血压和/之间是否存在关联。或死产。这项研究包括了1989年至2006年期间犹他州居民的633,000多例活产和死产，其中出生和胎儿死亡证明上记录的产妇住址在CWS的范围内。每个县超过97％的产妇地址都经过地理编码，然后在空间上链接到全州476个CWS服务区域的地理参考数据层和海拔数据。出于监管目的而收集的水质数据被用于估算每个标准煤的年平均砷含量；这些值将根据怀孕年份的头三个月和CWS为产妇的住所提供水来分配给出生和死胎。大多数住所（73.8％）的砷含量低于2.5微克每升（杯子/升）；仅有3.7％的住所中砷水平高于10 ig / L。砷浓度和SGA之间存在很小的关联，但在统计上具有显着意义。以<2.5杯/升为参考，当砷水平为5.1至9.9杯/升（p值0.03）时，SGA的调整比值比（aOR）为1.04（95％置信区间（CI）1.00、1.07）。 ，并且水平为10杯/升或更高（p值0.002）时，则为aOR 1.07（CI为1.03，1.12）。在砷水平从2.5到5杯/升时，SGA的增加很小，但无统计学意义（p值0.40）（aOR 1.01，CI 0.98、1.04）。未发现砷与妊娠相关的高血压有关，饮用水中低至中等水平的砷与死产之间也没有关联。另一个发现是，与海拔低于3,000英尺（英尺）的婴儿相比，居住在6,000英尺以上的女性，SGA的频率每升高1,000英尺，其aOR为1.91（CI 1.65，2.22）。

著录项

  • 作者

    Panichello, Janice Ann Davin.;

  • 作者单位

    The University of Utah.;

  • 授予单位 The University of Utah.;
  • 学科 Health Sciences Obstetrics and Gynecology.;Health Sciences Epidemiology.;Environmental Health.
  • 学位 Ph.D.
  • 年度 2011
  • 页码 81 p.
  • 总页数 81
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号