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Endocrine and immune function in songbirds exposed to p,p'-DDE and current-use pesticides in apple orchards.

机译:苹果园中暴露于p,p'-DDE和目前使用的农药的鸣禽的内分泌和免疫功能。

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This study investigated the associated effects of exposure to current-use orchard pesticides and p,p-DDE on concentrations of corticosterone in response to stress, circulating thyroid hormone levels and thyroid histology, the response to a phytohaemagglutinin (PHA) skin test as well as immune tissue histopathology in two species of passerines. Wild 16-day-old tree swallows (Tachycineta bicolor) and 12-day-old eastern bluebirds (Sialia sialis) from four apple orchards sprayed with pesticides and three non-sprayed reference sites in southern Ontario were tested during 2000–2001.; Nestling birds were exposed to as many as seven individual pesticide applications and up to five mixtures of pesticide sprays. Concentrations of p,p-DDE in tree swallow eggs ranged from 0.054 to 5.440 mg/kg (wet weight); bluebird eggs contained levels from 0.167 to 95.381 mg/kg (wet weight). Following a standardized handling stress coupled with adrenocorticotropic hormone (ACTH) challenge, tree swallow nestlings from sprayed orchards showed significantly higher levels of corticosterone relative to non-sprayed chicks; while bluebird chicks exhibited a significant negative association between circulating corticosterone and increasing concentration of p,p-DDE found in individual egg samples. (Abstract shortened by UMI.)
机译:这项研究调查了暴露于果园农药和p,p ' -DDE对应激,循环甲状腺激素水平和甲状腺组织学以及对植物血凝素的反应对皮质酮浓度的相关影响。 (PHA)皮肤检查以及两种雀形目鸟类的免疫组织病理学检查。来自四个喷洒了农药的苹果园和三个未喷洒的苹果园的野生16天大树燕子( Tachycineta bicolor )和12天大的东部蓝鸟( Sialia sialis )在2000-2001年期间对安大略省南部的参考地点进行了测试。雏鸟暴露于多达7种单独的农药施用和多达5种农药喷雾的混合物中。树吞卵中p,p ' -DDE的浓度为0.054至5.440 mg / kg(湿重);蓝鸟卵的含量为0.167至95.381 mg / kg(湿重)。在标准处理压力下加上促肾上腺皮质激素(ACTH)攻击后,喷洒果园中的树燕nest幼鸟的皮质酮水平明显高于未喷洒雏鸡。蓝鸟雏鸡的循环皮质酮与单个鸡蛋样本中p,p ' -DDE浓度增加之间存在显着的负相关。 (摘要由UMI缩短。)

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