• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Increasing the detection of adverse drug events in pediatric patients.
【24h】

Increasing the detection of adverse drug events in pediatric patients.

机译：在儿科患者中增加药物不良事件的检测。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Patient safety has received unprecedented attention over the past decade. Some of that attention has been focused on the occurrence and prevention of harm from Adverse Drug Events (ADEs). Between 19 and 61 percent of ADEs are preventable. In order to prevent ADEs, they must first be detected. Several methods have been used to detect ADEs, including voluntary reporting, intensified surveillance, and computerized monitoring. Computerized monitoring has been shown to be complimentary to other methods in detecting ADEs. However, very little research has been completed on this method in pediatrics.;Pediatric patients pose unique challenges and risks because of physiological immaturity, lack of testing and information on medications, availability of appropriate medication formulations and strengths, and incomplete cognitive and communication development.;This study examined the modification and implementation of an adult computerized ADE monitoring tool at one pediatric medical center. It was implemented into the daily practice of pharmacy operations without increasing the pharmacy resources. Pharmacists printed daily reports containing alerts of possible ADEs. They investigated each of the alerts and noted whether an ADE occurred and how much time was needed to investigate. The main objective of this study was to increase the detection of ADEs in the pediatric population.;Over the 12-week study, 181 ADEs were identified via the computerized monitoring tool. An additional 88 ADEs were voluntarily reported. Overall, this represented a rate of 6.6 ADEs per 100 admissions and 14.8 ADEs per 1,000 patient days. This result represented a significant increase in the detection of ADEs (p0.0001) as compared to the same timeframe from the previous year. The computerized monitoring tool had a positive predictive value (PPV) of 4.8 percent. It took an average of 6.1 minutes to investigate alerts associated with an ADE, which was significantly higher than the time it took to investigate alerts not associated with an ADE (p0.0001). Of the ADEs found with this tool, 10.5 percent were considered preventable.;The use of a modified computerized ADE monitoring tool in the pediatric environment increased the overall detection of ADEs and warrants continued research.
机译：在过去十年中，患者安全受到了前所未有的关注。其中一些注意力集中在不良药物事件（ADEs）的发生和预防上。 19％至61％的ADE是可以预防的。为了防止ADE，必须首先对其进行检测。已经使用了几种方法来检测ADE，包括自愿报告，强化监视和计算机监视。事实证明，计算机监控是检测ADE的其他方法的补充。但是，在儿科中对该方法的研究还很少完成。小儿患者由于生理上的不成熟，缺乏药物的测试和信息，适当的药物配方和强度的可用性以及不完全的认知和交流发展而面临独特的挑战和风险。 ；这项研究检查了一个儿科医疗中心的成人计算机化ADE监视工具的修改和实现。在不增加药房资源的情况下，已将其实施到药房日常操作中。药剂师打印每日报告，其中包含可能的ADE警报。他们调查了每个警报，并指出是否发生了ADE，以及需要多少时间进行调查。这项研究的主要目的是增加对儿科人群中ADEs的检测。在为期12周的研究中，通过计算机监控工具鉴定出181种ADEs。自愿报告了另外88个ADE。总体而言，这表示每100例入院6.6 ADEs和每1000病人日14.8 ADEs。与去年同期相比，该结果表明ADE的检出率显着提高（p <0.0001）。计算机监控工具的阳性预测值（PPV）为4.8％。调查与ADE相关的警报平均需要6.1分钟，这明显高于调查与ADE不相关的警报所花费的时间（p <0.0001）。用该工具发现的ADE中，有10.5％被认为是可预防的。;在儿科环境中使用改良的计算机化ADE监测工具，提高了ADE的整体检测率，值得继续研究。

著录项

  • 作者

    Atkinson, Sterling Dwight.;

  • 作者单位

    The University of Utah.;

  • 授予单位 The University of Utah.;
  • 学科 Health Sciences Medicine and Surgery.;Health Sciences Pharmacy.
  • 学位 M.S.
  • 年度 2010
  • 页码 70 p.
  • 总页数 70
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号