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Preventing cardiovascular disease in children and adolescents with type 2 diabetes mellitus.

机译：预防2型糖尿病儿童和青少年的心血管疾病。

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摘要

Problem: In the United States, there is an increasing incidence of diabetes mellitus type 2 (DMT2) in adolescents and children. Cardiovascular disease is a significant and common complication of DMT2. Therefore, it is imperative to identify cardiovascular risk factors and implement the appropriate intervention in this specific population with DMT2. The goal of this study is to determine the most effective method to screen for cardiovascular disease and identify an appropriate intervention in adolescents and children with DMT2 to slow or ideally halt the progression of cardiovascular disease.;Results: Forty articles were initially found, and 4 articles were used in the review.;Conclusions: From the articles reviewed in this study, it can be concluded that weight loss as achieved by exercise results in improved glycemic control, improved dyslipidemia, reduced BM1 and reduced waist circumference in adolescents with DMT1, and after one year of bariatric surgery (Roux en Y gastric bypass) there was evidence of remission of DMT2 in the majority of adolescent patients. Therefore, research is proposed to evaluate a comparison of whether weight loss or medical management is more effective in reducing cardiovascular disease as tested by utilizing an ultrasound to measure the carotid intima thickness in adolescents with DMT2 as a marker of atherosclerosis, providing a predictive marker of future cardiovascular disease.;Methods: The Weill Cornell Medical College Library Website was accessed, and the search engine PubMed was utilized. Several electronic journal articles were identified, reviewed, and included for discussion.
机译：问题：在美国，青少年和儿童中2型糖尿病（DMT2）的发病率正在增加。心血管疾病是DMT2的重要且常见的并发症。因此，必须在DMT2的这一特定人群中确定心血管危险因素并采取适当的干预措施。这项研究的目的是确定筛查心血管疾病的最有效方法，并为患有DMT2的青少年和儿童确定适当的干预措施，以减缓或理想地阻止心血管疾病的进展。结果：最初发现40篇文章，4结论：结论：从这项研究的文章中可以得出结论，通过运动实现的体重减轻可改善DMT1青少年的血糖控制，血脂异常，BM1减少和腰围减少，以及经过一年的减肥手术（Roux en Y胃绕道手术）后，大多数青少年患者都有DMT2缓解的证据。因此，提议进行研究以评估体重减轻或药物治疗是否能更有效地减少心血管疾病的比较，方法是利用超声波测量以DMT2作为动脉粥样硬化的标志物的青少年的颈动脉内膜厚度，从而提供预测性的标志物。方法：访问威尔康奈尔医学院图书馆网站，并使用搜索引擎PubMed。识别，审查并收录了几篇电子期刊文章，以供讨论。

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  • 作者

    Rampersaud, Nadia.;

  • 作者单位

    Weill Medical College of Cornell University.;

  • 授予单位 Weill Medical College of Cornell University.;
  • 学科 Health Sciences Epidemiology.
  • 学位 M.S.H.S.
  • 年度 2011
  • 页码 42 p.
  • 总页数 42
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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