• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Blood safety and resource allocation: Economic analyses of donated blood safety initiatives.
【24h】

Blood safety and resource allocation: Economic analyses of donated blood safety initiatives.

机译：血液安全和资源分配：捐赠血液安全计划的经济分析。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Risk management at any cost has become the apparent policy of blood banks and regulators because of transfusion-transmitted HIV and hepatitis. However, blood bank opinion leaders suggest economic analyses of new interventions are increasingly important for choosing between competing interventions. In this document we explore these issues and describe a new model to assess blood policy decisions. First, we provide a systematic review of blood supply policy evaluations and discuss improvements that can increase the usefulness of economic evaluation for decision makers. Researchers should: (1) provide more detail on cost parameters and methods used to obtain them; (2) adopt a clear analysis perspective relevant to decision makers that captures all important costs and consequences; (3) at minimum, conduct one-way sensitivity analyses; and (4) place greater reliance on graphical results presentation. Next, we describe a new model developed to evaluate factors that influence the safety, sufficiency, and cost of producing a blood supply. The model was developed using data from Blood Centers of the Pacific, San Francisco. The model is a cohort simulation that tracks blood donation beginning with the population of persons presenting for donation and ending with units of blood cleared for release to health care providers. We used the blood supply policy model to assess the impact of the U.S. Food and Drug Administration's expanded donor deferral criteria for European travel due to possible exposure to variant Creutzfeldt-Jakob disease. Expanded European travel deferral will lead to the permanent deferral of 3,271 donors (95% Confidence Range, 2,600–3,973 donors) reducing the supply of blood by 3,141 units out of an approximate 94,000 unit annual supply produced by this blood bank. The cost of each blood unit increases by {dollar}0.53 from the blood bank perspective and by {dollar}1.22 from the societal perspective. 2.8% of blood units that would have been available before the policy will be lost from the supply unless recruitment efforts are enhanced to bring in new donors and increase the frequency of repeat donation. This evaluation and other economic analyses provide a valuable approach for assessing the trade-off between safety and sufficiency for the blood supply.
机译：由于输血传播的艾滋病毒和肝炎，不惜一切代价进行风险管理已成为血库和监管机构的明显政策。但是，血库意见领袖认为，对新干预措施进行经济分析对于在竞争干预措施之间进行选择越来越重要。在本文中，我们探讨了这些问题，并描述了评估血液政策决策的新模型。首先，我们对血液供应政策评估进行了系统的回顾，并讨论了可以提高经济评估对决策者有用性的改进措施。研究人员应：（1）提供有关成本参数和获取方法的更多详细信息; （2）采用与决策者相关的清晰分析视角，以捕获所有重要成本和后果; （3）至少进行单向敏感性分析; （4）更加依赖图形结果表示。接下来，我们描述一种新模型，该模型用于评估影响血液供应的安全性，充足性和成本的因素。该模型是使用来自旧金山太平洋血液中心的数据开发的。该模型是一个队列模拟，它从献血的人群开始追踪献血，最后以清除的血液单位释放给医疗保健提供者来追踪献血。我们使用血液供应政策模型评估了美国食品药品监督管理局扩大的捐助者推迟欧洲旅行标准的影响，原因是可能暴露于不同的Creutzfeldt-Jakob疾病。欧洲旅行延期的扩大将导致3,271个捐助者的永久推迟（95％的置信度，2,600–3,973个捐助者）使该血库每年生产的大约94,000单位血液减少了3,141单位。从血库角度来看，每个血液单位的成本增加了{0.53}美元，从社会角度来看，则增加了{1.23}。除非加大招募工作以吸引新的捐助者并增加重复捐献的频率，否则在提供该政策之前本来可以使用的血液单位的2.8％将会失去供应。该评估和其他经济分析为评估血液供应的安全性和充足性之间的折衷提供了一种有价值的方法。

著录项

  • 作者

    Custer, Brian Scott.;

  • 作者单位

    University of Washington.;

  • 授予单位 University of Washington.;
  • 学科 Health Sciences Public Health.
  • 学位 Ph.D.
  • 年度 2003
  • 页码 118 p.
  • 总页数 118
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 预防医学、卫生学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号