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Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with 'low' versus 'high' hemoglobin using a dual stable isotope method.

机译：使用双重稳定同位素方法测定具有“低”血红蛋白与“高”血红蛋白的婴儿中固有标记的微囊化富马酸亚铁（散剂）中铁的吸收。

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Microencapsulated ferrous fumarate plus vitamins A and C (Sprinkles) in powder form is a new approach for ‘home-fortification’ of complementary foods. To determine iron (Fe) absorption from Sprinkles, 44 infants with hemoglobin concentration (Hb) 100g/L/L and 46 with Hb ≥ 100g/L were randomized to receive 30 or 45 mg of elemental Fe as 57Fe-labeled Sprinkles on 3 consecutive days. Additionally, a 58Fe tracer (0.2 mg as ferrous citrate) was infused intravenously (n = 46). Blood was drawn at baseline and 14 days later. Geometric mean Fe absorption was 8.7 and 7.0% in infants with Hb 100g/L, and 4.6 and 4.5% in infants with Hb ≥ 100g/L for the 30 and 45 mg doses, respectively. Percent Fe absorption was significantly higher in infants with Hb 100g/L as compared to infants with Hb ≥ 100g/L (p 0.0001), however there was no significant effect of dose (p = 0.35). Fe absorption from Sprinkles is regulated according to Fe needs.

机译：粉末状的微囊化富马酸亚铁加上维生素A和C（洒）是“补充食品”的“家庭强化”新方法。为了确定Sprinkles中铁的吸收，将44例血红蛋白浓度（Hb）<100g / L / L的婴儿和46例Hb≥100g / L的婴儿随机接受30或45 mg元素铁作为 57 铁标记的，连续3天洒。另外，静脉注入 58 Fe示踪剂（柠檬酸亚铁0.2 mg）（ n = 46）。在基线和14天后抽血。 Hb <100g / L的婴儿在30和45 mg剂量下的几何平均铁吸收分别为8.7％和7.0％，Hb≥100g / L的婴儿分别为4.6和4.5％。 Hb <100g / L的婴儿与Hb≥100g / L的婴儿相比，Fe吸收百分比明显更高（ p <0.0001），但是剂量没有明显影响（ p = 0.35）。洒水中的铁吸收量根据铁的需要进行调节。

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作者
Tondeur, Melody Christina.;
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作者单位

University of Toronto (Canada).;

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授予单位 University of Toronto (Canada).;
学科 Health Sciences Nutrition.
学位 M.Sc.
年度 2003
页码 121 p.
总页数 121
原文格式 PDF
正文语种 eng
中图分类预防医学、卫生学;
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1. 1. Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method. 2. New approaches to iron fortification: roleo [J] . Tondeur MC, Schauer CS, Christofides AL, The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2004,第5期

机译：1.使用双重稳定同位素方法测定具有不同铁和血液学状况的婴儿中固有标记的微囊化富马酸亚铁（散剂）对铁的吸收。 2.铁质防御的新方法：角色
2. Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method. [J] . Tondeur MC, Schauer CS, Christofides AL, The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2004,第5期

机译：使用双重稳定同位素方法测定具有不同铁和血液学状况的婴儿中固有标记的微囊化富马酸亚铁盐（散剂）中铁的吸收量。
3. Iron supplementation of low-income infants: a randomized clinical trial of adherence with ferrous fumarate sprinkles versus ferrous sulfate drops. [J] . Geltman PL, Hironaka LK, Mehta SD, The Journal of pediatrics . 2009,第5期

机译：低收入婴儿的铁补充剂：富马酸亚铁洒与硫酸亚铁滴剂依从性的随机临床试验。
4. Multi‐micronutrient Sprinkles including a low dose of iron provided as microencapsulated ferrous fumarate improves haematologic indices in anaemic children: a randomized clinical trial [O] . Anna Christofides, Kwaku Poku Asante, Claudia Schauer, 2006

机译：微量微量营养素散剂包括微胶囊化的富马酸亚铁提供的低剂量铁可改善贫血儿童的血液学指标：一项随机临床试验
5. Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method [O] . Mélody C Tondeur, Claudia S Schauer, Anna L Christofides, 2004

机译：采用双稳态同位素法测定具有不同铁和血液学状态的婴幼儿中本质上标记的微胶囊化的铁料（洒）的铁吸收

Determination of iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with 'low' versus 'high' hemoglobin using a dual stable isotope method.

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