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Fatigue and prealbumin levels during the weaning process in long-term ventilated patients.

机译:长期通风的患者在断奶过程中的疲劳和白蛋白水平。

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The study addresses two conditions that afflict long-term ventilated adult patients during the weaning process: fatigue and protein calorie malnutrition. The majority of the study was conducted in a four-bed respiratory unit of a tertiary care, urban medical center over 15 months. Sixty-one patients were assessed non-randomly for the study. Of the 61 patients, 45 were disqualified and five were removed from the study. The 11 remaining patients were able to complete the protocol. Fatigue scores were measured using the numerical rating scale of the Lee Fatigue Scale and protein calorie malnutrition was measured using serum prealbumin levels. Levine's Principles of Conservation (energy and structural integrity) guided the analysis for the longitudinal, descriptive design of this study. Findings revealed that LTV patients had distinctive fatigue trends during the weaning course. Fatigue scores were lower in the morning and rose after a weaning trial. Certain factors affected fatigue trends. Patients having a rest period before a weaning trial and during a weaning trial helped to reduce fatigue. Findings revealed an inverse relationship between fatigue and energy as would be expected during the weaning process. Overall, patients in the study experienced moderate to severe fatigue and low to moderate energy throughout their entire weaning process. PAB levels did not have a statistically significant association with fatigue; however, emerging trends were noted on particular patients who had subnormal to critically low PAB levels. Essentially, “morning” fatigue levels rose as PAB levels dropped and lowered as PAB levels rose. Likewise, “morning” energy levels lowered as PAB levels dropped and raised as PAB levels rose.
机译:该研究针对断奶过程中困扰长期通气的成年患者的两种情况:疲劳和蛋白质卡路里营养不良。大部分研究在城市医疗中心三级护理的四张病床中进行了15个月。本研究随机评估了61名患者。在61名患者中,有45名被取消资格,其中5名被从研究中删除。其余11名患者能够完成方案。使用Lee Fatigue量表的数字评分量表测量疲劳评分,并使用血清白蛋白前水平测量蛋白质卡路里营养不良。莱文的保护原理(能量和结构完整性)指导了对这项研究的纵向描述性设计的分析。结果显示,LTV患者在断奶过程中有明显的疲劳趋势。疲劳评分在早晨较低,经过断奶试验后上升。某些因素影响了疲劳趋势。在断奶试验之前和断奶试验期间休息的患者有助于减轻疲劳。研究结果表明,在断奶过程中疲劳与能量之间呈反比关系。总体而言,研究对象在整个断奶过程中经历了中度至重度疲劳,能量低至中度。 PAB水平与疲劳无统计学意义;然而,对于那些PAB水平低于正常或严重偏低的患者,出现了新的趋势。本质上,“早晨”疲劳水平随着PAB水平的下降而上升,而随着PAB水平的上升而下降。同样,“早晨”的能量水平会随着PAB水平的下降而降低,并随着PAB水平的上升而升高。

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