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Towards an image-guided spinal surgical system using three-dimensional ultrasound: From concept to clinic.

机译:迈向使用三维超声的图像引导脊柱外科手术系统:从概念到临床。

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摘要

Three-dimensional ultrasound (3-D US) is finding a host of applications among the many surgical fields. Tracked, freehand 3-D US can be utilized in spinal surgery as a means to identify vertebral regions of interest and guide the surgeon towards the target prior to any incision being made. If 3-D US images are used to establish a transformation between the patient space in the OR and image space, other tracked instrumentation can then be introduced to further guide the surgeon during the procedure.; In this work, an optically-tracked device for acquiring 3-D US information was designed, constructed and calibrated to an accuracy of approximately 0.4 mm. The device subsequently was tested in an application for image-guided surgery of the spine. Using a surface-based image registration algorithm, US images were mapped to pre-operative CT images from the lumbar vertebrae of phantoms and humans.; This method of registration first requires segmentation of the vertebral regions of interest. The vertebral surfaces from CT and US images were extracted using an intensity-based method. A rigid image registration was performed using an independent implementation of the Iterative Closest Point (ICP) algorithm. Accuracy measures demonstrat ed that the vertebral surfaces can be aligned to millimetric levels of accuracy. When an accurate registration was achieved, the resultant transformation was able to predict the trajectory of a tracked tap for pedicle screw insertion. Results further indicated that the accuracy of registration is dependent upon the frequency of the US signal, the resolution of the CT images, and the intensity at which the surfaces are extracted; Prior to clinical use, future work is needed to determine the best combination of these parameters. This approach to image-guided spinal surgery may also be beneficial for other regions of the spine, such as the thoracic region, where obtaining clear fluoroscopic images for guidance is hindered by the anatomy. This study is the first of its kind, accurately mapping 3-D vertebral US to CT images with an independent measure of registration accuracy
机译:三维超声(3-D US)正在许多外科领域中找到许多应用。可以在脊柱外科手术中使用跟踪的徒手3-D US,以识别感兴趣的椎骨区域并在进行任何切口之前将外科医生引导至目标。如果使用3-D US图像在手术室中的患者空间和图像空间之间建立转换,则可以在手术过程中引入其他跟踪的仪器以进一步指导外科医生。在这项工作中,用于获取3-D美国信息的光学跟踪设备的设计,构造和校准精度约为0.4毫米。该设备随后在脊柱图像引导手术的应用中进行了测试。使用基于表面的图像配准算法,将US图像映射到来自幻影和人的腰椎的术前CT图像。这种配准方法首先需要分割感兴趣的椎骨区域。使用基于强度的方法从CT和US图像提取椎骨表面。刚性图像配准使用迭代最近点(ICP)算法的独立实现方式进行。精度测量表明,椎骨表面可以对齐到毫米级的精度。当实现精确配准时,所得的变换能够预测用于椎弓根螺钉插入的跟踪丝锥的轨迹。结果还表明,配准的准确性取决于US信号的频率,CT图像的分辨率以及提取表面的强度;在临床使用之前,需要进一步的工作来确定这些参数的最佳组合。这种用于图像引导的脊柱外科手术的方法对于脊柱的其他区域,例如胸腔区域,也可能是有益的,在该区域中,解剖学阻碍了获得清晰的透视图像以进行引导。这项研究是同类研究中的第一项,它通过独立测量配准精度将3-D椎体US准确映射到CT图像

著录项

  • 作者

    Muratore, Diane Marie.;

  • 作者单位

    Vanderbilt University;

  • 授予单位 Vanderbilt University;
  • 学科 Engineering Biomedical; Health Sciences Medicine and Surgery
  • 学位 Ph.D
  • 年度 2002
  • 页码 p.1449
  • 总页数 256
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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