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Design and Manufacture of a High-Precision Electron Bolus Device for Radiation Therapy

机译：一种用于放射治疗的高精度电子小丸装置的设计与制造

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摘要

This research investigated a novel design and manufacturing approach for customized radiation modulation devices. Traditional fabrication methods for an electron bolus (a radiation modulation device) have lower precision (mm resolution). The current fabrication method is costly due to the use of expensive equipment and the requirement for dedicated machinist. In addition, its ecological impact is high due to higher material usage. In this research, the fused deposition modeling (FDM) technique was used to develop a hollow bottle-like electron bolus design with higher precision (?m resolution). The new design requires less amount of material, cost, and build time as compared to the traditional design and manufacturing method. A design of experiments approach was implemented to observe the effect of different input factors on the radiation modulation properties. These factors include bolus material, manufacturing orientation, loading force, and bolus wall thickness. The two materials used in this study were polycarbonate (PC), and acrylonitrile butadiene styrene (ABS). Bolus wall thickness of 1mm and 3mm was used to evaluate differences in radiation profiles. The boluses were subjected to high radiation doses and mechanical loads to check for dimensional deformations and impact on subsequent radiation profiles. The dimensional deviation analysis performed by comparing the cloud points of the bolus geometry pre and post radiation exposure indicated no significant differences. The flexural mechanical loading test demonstrated that the ABS material had lower deformation as compared to the PC. Finite element analysis of the bolus showed consistent results with mechanical loading tests. This research lays the foundation for the design and manufacture of next generation radiation modulation devices to be used in cancer therapy.
机译：这项研究调查了定制辐射调制设备的新颖设计和制造方法。电子团块（辐射调制装置）的传统制造方法具有较低的精度（毫米分辨率）。由于使用昂贵的设备以及需要专门的机械师，当前的制造方法成本很高。另外，由于较高的材料用量，其对生态的影响很大。在这项研究中，熔融沉积建模（FDM）技术被用于开发具有更高精度（？m分辨率）的空心瓶状电子弹丸设计。与传统设计和制造方法相比，新设计需要更少的材料，成本和制造时间。设计了一种实验方法，以观察不同输入因子对辐射调制特性的影响。这些因素包括弹丸材料，制造方向，加载力和弹丸壁厚。本研究中使用的两种材料是聚碳酸酯（PC）和丙烯腈丁二烯苯乙烯（ABS）。丸壁厚度分别为1mm和3mm来评估辐射曲线的差异。将大剂量的团块置于高辐射剂量和机械载荷下，以检查尺寸变形和对后续辐射轮廓的影响。通过比较大剂量几何图形在辐射暴露前后的浊点进行的尺寸偏差分析表明没有显着差异。弯曲机械载荷测试表明，与PC相比，ABS材料的变形较小。弹丸的有限元分析显示与机械负载测试一致的结果。这项研究为癌症治疗中使用的下一代辐射调制设备的设计和制造奠定了基础。

著录项

  • 作者

    Aldawood, Faisal Khaled.;

  • 作者单位

    North Carolina Agricultural and Technical State University.;

  • 授予单位 North Carolina Agricultural and Technical State University.;
  • 学科 Industrial engineering.
  • 学位 M.S.
  • 年度 2016
  • 页码 59 p.
  • 总页数 59
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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