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首页> 外文学位 >Restenotic outcomes and medical care costs following percutaneous transluminal coronary angioplasty with and without stent.
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Restenotic outcomes and medical care costs following percutaneous transluminal coronary angioplasty with and without stent.

机译：在有或没有支架的情况下进行经皮腔内冠状动脉成形术后的再狭窄结果和医疗费用。

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摘要

The purpose of the present study was to compare restenosis rates (repeat PTCA, coronary artery bypass grafting, or myocardial infarction) and medical care costs during one-year following stent PTCA and non-stent PTCA. Most studies on stents in PTCA have been limited to less than one-year of follow-up or to regional samples. A national claims database covering 1.7 million lives was used to identify 1,367 patients with PTCA during 1995 and no PTCA during the prior year. Stents were received by 304 of 1,367 patients. Chi-square analysis showed that there was no significant difference in the proportion of patients who experienced symptomatic restenosis (stent = 16.1% and non-stent = 20.1%, p = 0.12). Symptomatic restenosis was defined as occurrence of any of the following events: myocardial infarction (MI), repeat PTCA (stent or non-stent), or coronary artery bypass graft (CABG). There was no statistically significant difference between the stent PTCA and non-stent PTCA groups in proportions of patients experiencing MI, CABG, or repeat PTCA during the one-year follow-up period. Multivariate logit models were developed to evaluate the influence of stent use on probabilities of MI, CABG, repeat PTCA after controlling for gender, age, comorbidities and prior year hospital utilizations. After controlling for covariates, there was no statistically significant effect of stent use on probabilities of symptomatic restenosis, MI, CABG, or repeat PTCA during the one-year follow-up period. Although, there was no significant difference in mean one-year follow-up medical care costs, the mean total medical care costs including costs of initial PTCA was significantly higher for stent PTCA patients as compared non-stent PTCA patients. Multiple regressions after controlling for gender, age, comorbidities and prior year hospital utilizations further confirmed that there was no significant difference in one-year follow-up medical costs between stent PTCA and non-stent PTCA patients, although one-year total medical care costs including costs of initial PTCA was significantly higher for stent PTCA patients as compared to non-stent PTCA patients.
机译：本研究的目的是比较支架PTCA和非支架PTCA一年后的再狭窄率（重复PTCA，冠状动脉搭桥术或心肌梗塞）和医疗费用。 PTCA中对支架的大多数研究仅限于不到一年的随访或局部样本。 1995年，一个覆盖170万条生命的国家索赔数据库用于识别1,367例PTCA患者，而在上一年没有PTCA。 1,367例患者中有304例接受了支架。卡方分析显示，发生症状性再狭窄的患者比例没有显着差异（支架= 16.1％，非支架= 20.1％，p = 0.12）。有症状的再狭窄被定义为发生以下任何事件：心肌梗塞（MI），重复PTCA（支架或非支架）或冠状动脉搭桥术（CABG）。在一年的随访期间，支架PTCA和非支架PTCA组之间在发生MI，CABG或重复PTCA的患者中所占的比例没有统计学上的显着差异。建立了多变量logit模型以评估支架使用对控制性别，年龄，合并症和前一年医院使用率后MI，CABG，重复PTCA概率的影响。在控制协变量之后，在一年的随访期内，支架使用对症状性再狭窄，MI，CABG或重复PTCA的概率没有统计学上的显着影响。尽管平均一年的随访医疗费用没有显着差异，但与非支架PTCA相比，支架PTCA患者的平均总医疗费用（包括初始PTCA费用）明显更高。在控制了性别，年龄，合并症和前一年的医院使用率之后的多元回归进一步证实，尽管一年的总医疗费用为支架PTCA与非支架的PTCA患者之间的一年随访医疗费用没有显着差异。与非支架PTCA患者相比，支架PTCA患者包括初始PTCA的费用要高得多。

著录项

  • 作者

    Sen, Shuvayu Sankar.;

  • 作者单位

    Purdue University.;

  • 授予单位 Purdue University.;
  • 学科 Health Sciences Pharmacy.
  • 学位 Ph.D.
  • 年度 2001
  • 页码 152 p.
  • 总页数 152
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药剂学;
  • 关键词

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