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The effect of glucosamine sulfate supplementation on serum copper, zinc, and C-reactive protein in patients with degenerative joint disease

机译：补充硫酸氨基葡萄糖对退行性关节病患者血清铜，锌和C反应蛋白的影响

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摘要

Serum copper, zinc, C-reactive protein and 3-day diet records were analyzed pre- and post-supplementation with 1500 mg glucosamine sulfate (GS)/day for 12-weeks. Degenerative joint disease (DJD) patients (men = 17; women = 11), 31--64 years, were randomly assigned to treatment or control groups. Serum copper and zinc were analyzed by atomic absorption spectrophotometry. Serum C-reactive protein was analyzed by rate nephelometry. Diets were analyzed by the Food Processor program.;There were no significant differences in the three serum variables pre- and post-supplementation with GS. Females had significantly lower intakes of dietary copper and zinc compared to the normal reference values. Men had lower than the recommended dietary intakes of copper and zinc, although these were not statistically significant. There were no correlations between dietary and serum copper and dietary and serum zinc. Based on this study, GS has no apparent effect on serum copper, zinc, and C-reactive protein.
机译：在补充之前和之后每天用1500 mg硫酸葡萄糖胺（GS）/每天12周来分析血清铜，锌，C反应蛋白和3天饮食记录。年龄在31--64岁的退行性关节疾病（DJD）患者（男性= 17;女性= 11）被随机分配至治疗组或对照组。用原子吸收分光光度法分析血清铜和锌。通过速率比浊法分析血清C反应蛋白。通过食品加工程序对饮食进行了分析。补充GS前后，三个血清变量无显着差异。与正常参考值相比，女性的饮食中铜和锌的摄入量显着降低。男性的饮食中铜和锌的摄入量低于建议的摄入量，尽管这些在统计上并不显着。饮食和血清铜与饮食和血清锌之间没有相关性。根据这项研究，GS对血清铜，锌和C反应蛋白没有明显作用。

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  • 作者

    Carson, Diane Elizabeth.;

  • 作者单位

    California State University, Long Beach.;

  • 授予单位 California State University, Long Beach.;
  • 学科 Nutrition.;Public health.
  • 学位 M.S.
  • 年度 2000
  • 页码 63 p.
  • 总页数 63
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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