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首页> 外文学位 >Biaxial nonlinear elastic response of the human lumbar annulus fibrosus and its role in the determination of a physiologically relevant constitutive relation.
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Biaxial nonlinear elastic response of the human lumbar annulus fibrosus and its role in the determination of a physiologically relevant constitutive relation.

机译：人腰椎环纤维的双轴非线性弹性响应及其在确定生理相关本构关系中的作用。

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摘要

The intervertebral disc is known to be a primary cause in many cases of low back pain, and an estimated 4.1 million Americans report intervertebral disc disorders annually. Knowledge of the mechanical behavior of the annulus is critical to understanding its relation to disc disorder. However, the annulus is a complex orthotropic material whose principal directions possess dramatically different stiffnesses, and as yet a three-dimensional predictive model for the annulus has not been established. While the annulus fibrosus is in a state of biaxial tension in vivo, no experiment to date has examined the behavior of the annulus in this state. A biaxial testing fixture was designed, built, and used to perform experiments on a thin sheet of annulus fibrosus. Uniaxial tension tests were also performed. The results were used to examine the relative importance of uniaxial and biaxial tensile data in the determination of a physiologically relevant strain energy function and to determine a rational approximation to the in-plane orthotropic elastic strain energy of the tissue in the physiologic domain. A powerful technique that simultaneously fits data from several biaxial experiments was utilized to determine possible strain energy functions. Both population and individual fits were calculated, and both polynomial and exponential forms of the strain energy function were examined.;It was determined that polynomial and exponential expressions fit the data equally well within the region of the stress-strain space over which they were calculated. The region of the stress-strain space covered by the biaxial tests was found to be different from that covered by the uniaxial tests and the strain energy functions determined by the different datasets were dissimilar. Uniaxial data, therefore, may not be used to predict the behavior of the annulus in biaxial tension. Since biaxial tests cover a more physiologically relevant domain, further study of the biaxial behavior of the annulus, and the adoption of a strain energy function based solely on biaxial data, is indicated.
机译：已知椎间盘是许多下腰痛病例的主要原因，估计每年有410万美国人报告椎间盘疾病。了解环的机械行为对于理解其与椎间盘疾病的关系至关重要。然而，环是一种复杂的正交各向异性材料，其主要方向具有截然不同的刚度，并且尚未建立用于环的三维预测模型。当纤维环在体内处于双轴张力状态时，迄今为止尚无实验检查这种状态下环的行为。设计，建造了双轴测试夹具，并将其用于在纤维环薄片上进行实验。还进行了单轴拉伸试验。结果用于检查单轴和双轴拉伸数据在确定生理相关应变能函数中的相对重要性，并确定在生理领域中组织的平面内正交各向异性弹性应变能的合理近似值。一种强大的技术可以同时拟合来自多个双轴实验的数据，用于确定可能的应变能函数。计算总体拟合和个体拟合，并检查应变能函数的多项式和指数形式;确定多项式和指数表达式在计算它们的应力-应变空间区域内均等地拟合数据。发现双轴试验所覆盖的应力-应变空间区域与单轴试验所覆盖的区域不同，并且由不同数据集确定的应变能函数是不同的。因此，单轴数据可能无法用于预测双轴张力下环的行为。由于双轴测试涵盖了更多的生理相关领域，因此需要进一步研究瓣环的双轴行为，并采用仅基于双轴数据的应变能函数。

著录项

  • 作者

    Bass, Elisa Carolyn.;

  • 作者单位

    University of California, Berkeley.;

  • 授予单位 University of California, Berkeley.;
  • 学科 Mechanical engineering.;Mechanics.;Biomedical engineering.
  • 学位 Ph.D.
  • 年度 1999
  • 页码 109 p.
  • 总页数 109
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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