• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Experimental study and mathematical modeling of immobilized Klebsiella oxytoca for 2,3-butanediol production.
【24h】

Experimental study and mathematical modeling of immobilized Klebsiella oxytoca for 2,3-butanediol production.

机译：固定化产克雷伯菌产2,3-丁二醇的实验研究和数学模型。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

process employing calcium alginate immobilized Klebsiella oxytoca airlift bioreactor for continuous butanediol production is studied. Klebsiella oxytoca is a facultative anaerobe fermenting glucose to 2,3-butanediol which is a potentially valuable chemical feedstock. A dynamic mathematical model has been developed to simulate the operation of the continuous immobilized cell bioreactor. The model combines simultaneous diffusion and cell kinetics, as well as cell growth and maintenance/death. Bioenergetic principles, combined with mass balance and redox balance were employed to describe the anaerobic, oxygen limited and aerobic microbial rate processes. This model can predict reasonably well the dynamic of cell growth and death, glucose and oxygen consumptions, ethanol and butanediol productions as well as intraparticle radial cell distribution. The effects of glucose feed concentration, dilution rate on 2,3-butanediol concentration and productivity have been investigated experimentally. The mathematical model can predict reasonably these effects. A method has also been developed to determine the dynamic cell distribution within the calcium alginate gel bead. The procedures involve fixing, impregnating and thin sectioning of the gel bead. Sections of less than 0.5
机译：研究了利用藻酸钙固定化产氧克雷伯菌气提生物反应器连续生产丁二醇的工艺。产酸克雷伯菌是一种兼性厌氧菌，可将葡萄糖发酵成2,3-丁二醇，这是一种潜在有价值的化学原料。已经开发了动态数学模型来模拟连续固定细胞生物反应器的操作。该模型结合了同时扩散和细胞动力学，以及细胞生长和维持/死亡。利用生物能原理，结合质量平衡和氧化还原平衡来描述厌氧，氧受限和需氧微生物速率过程。该模型可以合理地预测细胞生长和死亡，葡萄糖和氧气消耗，乙醇和丁二醇产量以及颗粒内放射状细胞分布的动态。实验研究了葡萄糖进料浓度，稀释率对2,3-丁二醇浓度和生产率的影响。数学模型可以合理地预测这些影响。还开发了一种确定藻酸钙凝胶珠粒内动态细胞分布的方法。程序涉及固定，浸渍和切成薄片的凝胶珠。小于0.5的部分

著录项

  • 作者

    Lo, Waihung.;

  • 作者单位

    Purdue University.;

  • 授予单位 Purdue University.;
  • 学科 Chemical engineering.
  • 学位 Ph.D.
  • 年度 1991
  • 页码 170 p.
  • 总页数 170
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号