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Reproductive, hormonal and lactational responses in postpartum, fine-wool ewes and in virgin ewe lambs treated with ovine growth hormone

机译:用绵羊生长激素治疗的产后细羊毛母羊和初生母羊的生殖,激素和泌乳反应

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摘要

Eighteen mature fine-wool ewes nursing single offspring received daily injections (sc) of 0, 5, or 10 mg ovine growth hormone (oGH) from d 11-20 postpartum (PP). On d 11 and 20 PP, blood was collected before and for 8 h after treatment. Milk contituents were evaluated on d 21 PP. Serum insulin did not differ (P $>$.10) on d 11. On d 20, serum insulin was higher (P $<$.05) before treatment in both groups receiving oGH, although after treatment, serum insulin was comparable (P $>$.20) among treatments. Serum growth hormone (GH) on d 11 was similar (P $>$.20) among groups before treatment; however, 8 h after treatment a linear (L) dose-dependent increase (P $<$.01) was detected in GH-treated ewes. By d 20 PP, serum GH differed (P $<$.01) among groups. Ewes receiving 5 or 10 mg oGH produced more (P $<$.05) milk and milk fat compared with controls. A linear decrease (P =.10) was detected in interval from parturition to first observed estrus as oGH dosage increased (116, 108 and 102 $pm$ 6 d for 0, 5 and 10 mg groups, respectively). In a second trial, 30 6-mo-old fine-wool ewe lambs were allotted to three groups 1 mo before a fall breeding season. Treatments were of either 0, 2.5 or 5 mg oGH administered daily for 10 d and continued on alternate d for 20 d. Five ewes from each group were sampled for 8 h after treatment on d 0, 9, 19 and 29. After termination of treatment, ewes were exposed to fertile rams for a 34-d period. Ewe weights did not differ (P $>$.20) among groups during or following treatment. On d 0 and 29, serum insulin was similar (P $>$.20) among groups before and for 5 h after oGH administration; however, 6, 7 and 8 h after treatment, a dose-dependent linear increase (P $<$.10) was detected. Serum insulin differed (L, P $<$.01) before and after treatment on d 9. On d 19, serum insulin differed (P $<$.10) 2, 3, 6, 7 and 8 h after treatment among groups. Serum GH 1 h after oGH administration was higher (L, P $<$.01) in ewes receiving oGH and this difference continued through h 8. Serum GH was elevated (P $<$.01) on d 9, 19 and 29 in both GH-treated groups. Number of ewes cycling during treatment and breeding were similar (P $>$.20) among groups. Pregnancy rates were comparable in ewes receiving 0 (70%), 2.5 (80%) and 5 (60%) mg oGH.
机译:十八个成熟的细毛母羊哺乳后代从产后第11-20天每天注射(sc)0、5或10 mg绵羊生长激素(oGH)。在PP的第11天和第20天,在治疗之前和之后8小时收集血液。在d 21 PP上评估牛奶成分。第11天的血清胰岛素无差异(P $> $。10),第20天,接受oGH治疗的两组患者的血清胰岛素均较高(P $ <$。05),尽管治疗后血清胰岛素具有可比性( P $> $。20)。治疗前第11天的血清生长激素(GH)相似(P> 0.20)。然而,在处理后8小时,在GH处理的母羊中检测到线性(L)剂量依赖性增加(P $ <$。01)。到d 20 PP时,各组之间的血清GH差异(P $ <。0.01)。与对照相比,接受5或10毫克oGH的母羊产生的牛奶和乳脂更多(P $。05)。随着oGH剂量的增加(从0、5和10 mg组分别为116、108和102 $ pm $ 6 d),从分娩到首次观察到的发情之间的时间间隔内检测到线性下降(P = .10)。在第二次试验中,在秋季繁殖季节开始前1个月,将30只6个月大的细毛母羊羔羊分配给三组。每天给予0、2.5或5 mg oGH的治疗持续10 d,并在每隔d持续20 d。在治疗后第0、9、19和29天,从每组五只母羊采样8小时。治疗终止后,将母羊暴露于可育公羊34天。在治疗期间或之后,各组之间的母羊体重没有差异(P $> $。20)。在第0天和第29天,在给予oGH之前和之后5 h,各组的血清胰岛素相似(P> 0.20)。然而,在治疗后6、7和8小时,检测到剂量依赖性线性增加(P $ <。10)。第9天,治疗前后血清胰岛素差异(L,P $ <$。01)。在第19天,各组治疗后2、3、6、7和8小时血清胰岛素差异(P $ <。10)。 。接受oGH的母羊服用oGH后1 h的血清GH较高(L,P $ <$。01),这种差异持续到h8。在第9、19和29天,血清GH升高(P $ <$。01)。在两个GH治疗组中。各组之间在治疗和繁殖期间循环的母羊数量相似(P $> $。20)。接受0(70%),2.5(80%)和5(60%)oGH的母羊的怀孕率相当。

著录项

  • 作者

    Holcombe, Dale Wood.;

  • 作者单位

    New Mexico State University.;

  • 授予单位 New Mexico State University.;
  • 学科 Animal Physiology.;Animal sciences.
  • 学位 Ph.D.
  • 年度 1988
  • 页码 118 p.
  • 总页数 118
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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