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Characteristics and predictors of mortality and morbidity in critically ill patients with acute pulmonary embolism.

机译:重症急性肺栓塞患者死亡率和发病率的特征和预测指标。

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摘要

Objective To determine the characteristics and predictors of survival amongst critically ill patients with pulmonary embolism (PE).;Method Demographic, clinical, investigational and therapeutic data on 96 patients in adult ICUs diagnosed with PE, were collected. Mortality predictors were determined using bivariate and multivariate analysis.;Results The need for ionotropic support (B=- 0.293, p=0.003), early mechanical ventilation (B=- 0.198, p=0.043), active malignancy (B=0.280, p=0.003), prior PE (B=- 0.218, p=0.019) and Right bundle branch block (RBBB) (B=0.211, p=0.023) predicted hospital survival. Predictors of survival at 6 weeks and 6 months respectively were the use of oral anticoagulants (B=0.498, p=0.000 and B=0.476, p=0.000), mechanical ventilation (B=-0.311, p=0.001 and B=-0.376, p=0.000) and history of prior PEs (B=-0.226, p=0.010 and B=-0.213, p=0.016).;Conclusion The predictors of hospital survival are ionotropic support, mechanical ventilation, active malignancy, prior PEs and RBBBs. Prior PEs, mechanical ventilation and inability to use oral anticoagulants predict long term survival.
机译:目的确定重症肺动脉栓塞(PE)患者的特征和生存率。方法:收集96例成人PE患者的人口统计学,临床,研究和治疗资料。死亡率预测因素通过二元和多元分析确定。结果需要离子支持(B =-0.293,p = 0.003),早期机械通气(B =-0.198,p = 0.043),活动性恶性肿瘤(B = 0.280,p) = 0.003),先前的PE(B =-0.218,p = 0.019)和右束支传导阻滞(RBBB)(B = 0.211,p = 0.023)预测医院生存率。使用口服抗凝剂(B = 0.498,p = 0.000和B = 0.476,p = 0.000),机械通气(B = -0.311,p = 0.001和B = -0.376)分别是6周和6个月生存率的预测指标,p = 0.000)和既往PE的病史(B = -0.226,p = 0.010和B = -0.213,p = 0.016)。;结论医院生存的预测指标是离子支持,机械通气,活动性恶性肿瘤,既往PE和RBBB。先前的PE,机械通气和无法使用口服抗凝药可预测长期生存。

著录项

  • 作者

    Salim, Tanuja.;

  • 作者单位

    Rush University.;

  • 授予单位 Rush University.;
  • 学科 Medicine.
  • 学位 M.S.
  • 年度 2016
  • 页码 23 p.
  • 总页数 23
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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