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Adaptive and Socio-Emotional Functioning in Childhood Cancer Survivors: An Analysis Using the Kaiser Permanente Neurocognitive Late Effects Brief Assessment Battery.

机译:儿童癌症幸存者的适应和社会情感功能:使用Kaiser Permanente神经认知后期效应简要评估报告的分析。

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摘要

Childhood cancer is the leading cause of death by disease in children and adolescents (Askins & Moore, 2008; Haddy, Mosher, & Reaman, 2009). Treatment options include chemotherapy, radiation therapy, surgery, and/or other types of treatment such as bone marrow transplant (BMT), stem cell rescue and transplant, steroids, and immunotherapy. Despite these advances, there are negative side effects consequent to the neurotoxic exposure inherent to these methods.;Childhood cancer survivors may experience numerous and varied deficits, and outcome depends on various factors, including form of cancer, tumor size and location, treatment dosage, and complications. Research indicates difficulties with gross and fine motor coordination, executive function, non-verbal problem solving, memory, attention, processing speed, and working memory (Fennell & Butler, 2008; Semrud-Clikeman & Ellison, 2009). The present study aimed to focus on the impact on socio-emotional and adaptive functioning.;This study evaluated socio-emotional functions in 113 childhood cancer survivors assessed with the Kaiser Permanente Neurocognitive Late-Effects Brief Assessment Battery (KP-NCLE). The relationship between treatment dosage and daily functioning based on parent behavioral rating data was analyzed. Results show a significant effect of treatment risk on Hyperactivity. Furthermore, all standardized scores were within normal limits. Although this group was functioning at non-clinical levels at initial assessment, these results lend support for annual testing as part of survivorship planning for pediatric cancer survivors in order to identify and mitigate symptoms of cognitive, behavioral and emotional dysregulation.
机译:儿童癌症是导致儿童和青少年因疾病死亡的主要原因(Askins和Moore,2008年; Haddy,Mosher和Reaman,2009年)。治疗选择包括化学疗法,放射疗法,手术和/或其他类型的疗法,例如骨髓移植(BMT),干细胞抢救和移植,类固醇和免疫疗法。尽管取得了这些进展,但这些方法固有的神经毒性暴露仍会带来不利的副作用。儿童癌症幸存者可能会经历多种多样的缺陷,其结局取决于各种因素,包括癌症的形式,肿瘤的大小和位置,治疗剂量,和并发症。研究表明,在粗略和精细的运动协调,执行功能,非语言问题解决,记忆,注意力,处理速度和工作记忆方面存在困难(Fennell&Butler,2008; Semrud-Clikeman&Ellison,2009)。本研究的重点是对社会情感和适应功能的影响。本研究评估了通过Kaiser Permanente神经认知后期效应简短评估电池组(KP-NCLE)评估的113名儿童癌症幸存者的社会情感功能。根据父母行为评分数据分析了治疗剂量与日常功能之间的关系。结果显示治疗风险对多动症有显着影响。此外,所有标准分数均在正常范围内。尽管该组在初步评估时处于非临床水平,但这些结果为年度检测提供了支持,作为儿童癌症幸存者生存计划的一部分,以识别和缓解认知,行为和情绪失调的症状。

著录项

  • 作者

    Wells, Vanessa A.;

  • 作者单位

    The Chicago School of Professional Psychology.;

  • 授予单位 The Chicago School of Professional Psychology.;
  • 学科 Oncology.
  • 学位 Psy.D.
  • 年度 2015
  • 页码 99 p.
  • 总页数 99
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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