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On the design of a biodegradable POC-HA polymeric cardiovascular stent.

机译:关于可生物降解的POC-HA聚合物心血管支架的设计。

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摘要

The current state of the art in coronary stent technology is mainly populated by metallic stents usually coated with certain drugs to increase biocompatibility, even though experimental biodegradable stents have appeared in the horizon. To design stents from biodegradable polymers one must accurately characterize their mechanical behavior for analysis and optimization.;This manuscript presents the process for evaluating the material properties for biodegradable biocompatible POC-HA polymeric composite, techniques for developing the stent models for finite element analysis, and development of material models for finite element analysis. The developed material models were utilized in finite element analysis to evaluate the suitability of the POC-HA material for coronary stent application. In addition, the advantages of using femtosecond laser machining to fabricate the POC-HA stent will be discussed. The methodology presented can be applied in the development of a biocompatible and biodegradable polymeric stent.
机译:冠状动脉支架技术的当前水平主要由通常涂覆有某些药物以提高生物相容性的金属支架组成,即使实验可生物降解的支架已经出现。要使用可生物降解的聚合物设计支架,必须准确表征其机械性能以进行分析和优化。;该手稿介绍了评估可生物降解的生物相容性POC-HA聚合物复合材料的材料性能的过程,开发用于有限元分析的支架模型的技术以及开发用于有限元分析的材料模型。开发的材料模型用于有限元分析,以评估POC-HA材料在冠状动脉支架应用中的适用性。另外,将讨论使用飞秒激光加工来制造POC-HA支架的优势。提出的方法可用于开发生物相容性和可生物降解的聚合物支架。

著录项

  • 作者

    Ponkala, Joonas Ilmari.;

  • 作者单位

    The University of Texas at Arlington.;

  • 授予单位 The University of Texas at Arlington.;
  • 学科 Engineering Biomedical.;Engineering Mechanical.
  • 学位 M.S.
  • 年度 2009
  • 页码 88 p.
  • 总页数 88
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物医学工程;机械、仪表工业;
  • 关键词

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