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Individual analysis of T2*-weighted gradient echo imaging in asymptomatic and symptomatic athletes.

机译：对无症状和有症状运动员进行T2 *加权梯度回波成像的个体分析。

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Mild traumatic brain injury (mTBI), is a commonly occurred sports-related injury, especially in contact sports like football and soccer. Hemorrhage will appear as hypointense lesions on T2 *-weighted images, resulting from mTBI. Thus, T 2*-weighted gradient echo pulse sequence can be used to generate magnitude susceptibility-weighted (SW) images, and to further detect negative intensity changes of different regions of interests (ROIs) inside human brains. Our goal was to investigate how the ROI-specific intensity changes in each individual sports athlete over a single competition season and to interrogate whether these changes are correlated with repetitive subconcussive or concussive events. After a pipeline of processing steps on the magnitude SW images, three separate statistical analyses were applied to detect cerebral regions that are showing negative changes during the participation. Results are implying that a few statistically significant decreases were found in some certain ROIs among several sports athletes while most of the collision sports athletes exhibited no magnitude SW image changes during their own competition season. It is also shown that T2*-weighted imaging, while not ideal for asymptomatic athletes, can reveal changes in some mTBI subjects.

机译：轻度创伤性脑损伤（mTBI）是与运动相关的常见伤害，尤其是在足球和足球等接触性运动中。出血将由mTBI在T2 *加权图像上显示为低血性病变。因此，T 2 *加权梯度回波脉冲序列可用于生成幅度磁化加权（SW）图像，并进一步检测人脑内部不同兴趣区域（ROI）的负强度变化。我们的目标是调查单个运动员在单个比赛季节内ROI特定强度的变化，并询问这些变化是否与重复性脑震荡或脑震荡事件相关。在对幅度SW图像进行一系列处理步骤之后，应用了三个单独的统计分析来检测在参与过程中显示出负变化的大脑区域。结果表明，在几名体育运动员中，某些特定的投资回报率出现了统计学上的显着下降，而大多数碰撞体育运动员在自己的比赛季节中并未表现出幅度的SW图像变化。还显示，T2 *加权成像虽然对于无症状运动员而言并不理想，但可以揭示某些mTBI受试者的变化。

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作者
Mao, Xianglun.;
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作者单位

Purdue University.;

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授予单位 Purdue University.;
学科 Electrical engineering.;Kinesiology.;Biomedical engineering.
学位 M.S.E.C.E.
年度 2015
页码 60 p.
总页数 60
原文格式 PDF
正文语种 eng
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Individual analysis of T2*-weighted gradient echo imaging in asymptomatic and symptomatic athletes.

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