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首页> 外文学位 >Feasibility of RDS, Effectiveness of Risk-Reduction-Counseling and Testing, and Factors Associated with Loss-to-Follow-Up in an Intervention Study for Men Who Have Sex with Men in Nanjing.
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Feasibility of RDS, Effectiveness of Risk-Reduction-Counseling and Testing, and Factors Associated with Loss-to-Follow-Up in an Intervention Study for Men Who Have Sex with Men in Nanjing.

机译：在南京对男男性接触者进行干预研究中，RDS的可行性，降低风险的咨询和测试的有效性以及与失访相关的因素。

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摘要

Background: Respondent-driven-sampling (RDS) has been recognized as a method for sampling from most hard-to-reach populations. Meanwhile, loss to follow up of the participants in follow up studies usually reduces the validity of the association measured in observational studies, and this problem cannot be overcame through data analysis.;Methods: In a cross sectional study in Nanjing city of Jiangsu province of China, 430 MSM were recruited including 9 seeds in 14 weeks of study period using RDS. Information regarding socio-demographic characteristics and sexual risk behavior were collected and testing was done for HIV and syphilis. Duration, completion, participant characteristics and the equilibrium of key factors were used for assessing feasibility of RDS. All the HIV negative participants were followed up at 6, 12 and 18 months to evaluate behavioral changes after counseling to reduce risk behaviors. Logistic regression was performed to identify the factors correlated with loss to follow up.;Results: In the study sample, adjusted HIV and syphilis prevalence were 6.6% and 14.6% respectively, whereas HIV incidence was 5.2 per 100 person-years. The incidence was 3.8 during six to 12 months, and 1.1 during 12 to 18 months. Although there was a tendency for recruitment within the same self-identified group, considerable cross-group recruitment was also seen. During the study period, the reported unprotected anal intercourse (UAI) significantly decreased from 60.9% to 42.9%. The proportion of participants who had one or no partner significantly increased from 40.9% to 48.0%. The study also found that some risk behaviors decreased between baseline and 12 months, followed by a slight increase between 12 and 18 months. In addition, loss to follow up for the MSM study in Nanjing was associated with younger age, small social network, lower education, and non-official residence in Jiangsu.;Conclusion: RDS was found to be a potential efficient and feasible sampling method for recruiting a diverse sample of MSM in a reasonable time. Reductions in UAI can be achieved through counseling and testing, but may wane over time. The factors correlated with loss-to-follow-up found in of our study may be helpful to increase the retention rate of future cohort studies.
机译：背景：受访者驱动的抽样（RDS）被认为是从大多数难以覆盖的人群中抽样的方法。同时，随访研究中参与者的失访通常会降低观察研究中所测得的关联的有效性，并且无法通过数据分析来解决这个问题。方法：在江苏省南京市进行的一项横断面研究中在中国，使用RDS在研究的14周内招募了430个MSM，包括9颗种子。收集了有关社会人口统计学特征和性风险行为的信息，并对艾滋病毒和梅毒进行了检测。持续时间，完成度，参与者特征和关键因素的平衡被用于评估RDS的可行性。在咨询降低风险行为后，对所有HIV阴性参与者进行了6、12和18个月的随访，以评估其行为变化。结果：在研究样本中，调整后的HIV和梅毒患病率分别为6.6％和14.6％，而HIV发病率为每100人年5.2。在6至12个月内发病率为3.8，在12至18个月内发病率为1.1。尽管在同一自我认同的群体中存在招聘的趋势，但也看到了相当多的跨群体招聘。在研究期间，报告的未保护肛交（UAI）从60.9％显着降低到42.9％。没有伴侣或没有伴侣的参与者比例从40.9％显着增加到48.0％。该研究还发现，一些风险行为在基线到12个月之间有所降低，然后在12到18个月之间略有增加。此外，在南京进行MSM研究的后续损失与年龄较小，社交网络少，受教育程度低以及江苏省的非官方居住有关。结论：RDS被认为是一种潜在的高效可行的抽样方法。在合理的时间内收集各种MSM样本。 UAI的减少可以通过咨询和测试来实现，但随着时间的流逝可能会逐渐减少。在我们的研究中发现的与随访失访相关的因素可能有助于提高未来队列研究的保留率。

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  • 作者

    Tang, Weiming.;

  • 作者单位

    University of California, Los Angeles.;

  • 授予单位 University of California, Los Angeles.;
  • 学科 Health Sciences Epidemiology.;GLBT Studies.;Psychology Counseling.
  • 学位 Ph.D.
  • 年度 2014
  • 页码 121 p.
  • 总页数 121
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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