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Investigations of Anticancer Compounds from Camellia sinensis: Green, Black, and White Tea.

机译：茶树抗癌化合物的研究：绿茶，红茶和白茶。

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摘要

Natural compounds have known to treat and cure diseases and ailments since the beginning of time. The incidences of carcinoma cases increasingly grow every year. Since cancer cells and tumors are becoming more multidrug resistant there is a great demand for new and more secondary compounds, which are synthesized from plant and account for more than 50% of anti-cancer compounds. Medical research and clinical trials with Camellia sinensis has revealed various health benefits including positive effects on cholesterol levels, weight loss, and potential anti-cancer properties. My objectives were to screen Camellia sinensis: green, black, and white tea for possible cytotoxic activity against breast and colon carcinoma cell lines, quantify growth inhibition and cell viability. Camellia sinensis: Green, black, and white tea crude extracts were tested against human colon carcinoma cell lines HT-29, Colo-320, and breast carcinoma cell line BT 20. Alamar blue was used to analyze cell viability and toxicity after 48 hours. Camellia sinensis showed the most growth inhibition against all carcinoma cell lines at the maximum concentration of 25mug/ml.
机译：自从开始以来，就已经知道天然化合物可以治疗和治愈疾病。癌病例的发病率每年都在增长。由于癌细胞和肿瘤变得越来越具有多药耐药性，因此迫切需要新的和更多的次生化合物，这些化合物是由植物合成的，占抗癌化合物的50％以上。茶树的医学研究和临床试验显示了各种健康益处，包括对胆固醇水平的积极影响，减肥和潜在的抗癌特性。我的目标是筛选山茶：绿茶，红茶和白茶对乳腺癌和结肠癌细胞系可能的细胞毒活性，量化生长抑制和细胞活力。茶花：对人结肠癌细胞株HT-29，Colo-320和乳腺癌细胞株BT 20进行了绿茶，红茶和白茶粗提物的测试。阿拉玛蓝用于分析48小时后的细胞活力和毒性。茶花在最大浓度为25mug / ml时对所有癌细胞系的生长抑制最大。

著录项

  • 作者

    White, Rachel A.;

  • 作者单位

    Tennessee State University.;

  • 授予单位 Tennessee State University.;
  • 学科 Health Sciences Pharmacology.;Health Sciences Alternative Medicine.;Health Sciences Oncology.
  • 学位 M.S.
  • 年度 2014
  • 页码 8 p.
  • 总页数 8
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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