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Quaternary lyme disease: Symptomatology, epidemiology and anthropology of an emerging disease.

机译:第四季莱姆病:一种新兴疾病的症状,流行病学和人类学。

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摘要

In a press release dated August 19, 2013, the United States Centers for Disease Control and Prevention (CDC) changed its annual estimate of Lyme disease cases from approximately 30,000 to 300,000. This number is 10 times the previous projections, making Lyme disease the most widely reported vector-borne disease in the United States. The CDC estimates that between 10 and 20 percent of Lyme disease patients go on to develop a cadre of post-treatment Lyme disease symptoms that typically resolve within six months of treatment. The agency considers these symptoms to be unrelated to an active Lyme disease infection. A growing number of individuals report that this post-treatment Lyme disease syndrome extends beyond the interval suggested by CDC. This study evaluates 220 adult male and female individuals who report experiencing post-treatment Lyme disease syndrome symptomatology beyond the CDC suggested six-month interval. Based on the symptomatological, epidemiological, social and behavioral characteristics of this study group, this study proposes a new category of Lyme disease called quaternary Lyme disease that includes the symptomatology of post-treatment patients and is inclusive of individuals who experience these symptoms beyond the typical six-month timeframe. The study also proposes a rudimentary algorithm to assist clinicians in determining if patients risk profiles suggests quaternary Lyme disease. The purpose of this is to help identify patients who may need additional palliative care. It is also intended to aid in the identification of individuals who are potential research participants in order for biomedical science to perform more in depth research into the etiology behind persistent symptoms associated with post-treatment Lyme disease.
机译:在2013年8月19日的新闻稿中,美国疾病控制与预防中心(CDC)将莱姆病的年度估计数从大约30,000更改为300,000。这个数字是先前预测的10倍,使莱姆病成为美国报道最广泛的媒介传播疾病。 CDC估计,有10%到20%的莱姆病患者会继续发展出一批​​治疗后的莱姆病症状,这些症状通常会在治疗后六个月内消失。该机构认为这些症状与活跃的莱姆病感染无关。越来越多的人报告说,这种治疗后的莱姆病综合征超出了CDC建议的间隔。这项研究评估了220名成年男性和女性个体,这些个体报告在CDC建议的六个月间隔后报告有治疗后的莱姆病综合征症状。根据该研究组的症状,流行病学,社会和行为特征,本研究提出了一种新的莱姆病类别,称为四级莱姆病,其中包括治疗后患者的症状,并且包括那些经历了典型症状以外的症状的个体六个月的时间范围。这项研究还提出了一种基本算法,可以帮助临床医生确定患者的风险状况是否提示四级莱姆病。这样做的目的是帮助确定可能需要额外姑息治疗的患者。它还旨在帮助识别潜在的研究参与者,以便生物医学科学对与治疗后的莱姆病相关的持续症状背后的病因进行更深入的研究。

著录项

  • 作者

    Darcy, John Martin, II.;

  • 作者单位

    State University of New York at Binghamton.;

  • 授予单位 State University of New York at Binghamton.;
  • 学科 Health Sciences Epidemiology.;Health Sciences Public Health.;Health Sciences Medicine and Surgery.
  • 学位 Ph.D.
  • 年度 2014
  • 页码 256 p.
  • 总页数 256
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 水产、渔业;
  • 关键词

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