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Demineralization and remineralization at proximal lesion sites: Digital Imaging Fiber-Optic Transillumination (DIFOTI), digital radiography, with subtraction technique.

机译:近端病变部位的脱矿质和再矿化:数字成像光纤透射(DIFOTI),数字射线照相术以及减影技术。

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摘要

Introduction. Dental caries involves the demineralization of the hydroxyapatite tooth structure. However, prior to cavitations, this process can be reversed via remineralization. Early detection of the carious lesion and monitoring of the progression of the lesion over time are key factors in the management of the disease. Dental radiograph has been the most common tool for routine proximal caries examination. Intraoral dental radiography is the current diagnostic standard of care. Devices such as Digital Imaging Fiber-Optic Trans Illumination (DIFOTI) have been introduced to improve early detection of carious lesions.;Objective. The aims of the study were (1) to determine if Digital Imaging Fiber-Optic Trans Illumination (DIFOTI) can detect remineralization at proximal enamel lesions; (2) to compare the ability of DIFOTI and digital radiography in the detection of demineralization and remineralization at proximal enamel lesions with use of digital subtraction in conjunction with both imaging modalities.;Material and methods. At alpha=0.025, beta=80%, thirty intact human premolars randomly arranged in pair. Images of sample teeth were taken with DIFOTI and digital radiographs before demineralization process and every week during demineralization until demineralization were detected with DIFOTI and digital radiograph. Sample set were placed into a demineralization solution that simulates the in vivo demineralization process which consisted of a saturated hydroxyapaptite/0.1 M lactic acid in 1% Carbopol C907 solution at a pH of 5 at 37°C. Following the completion of the demineralization, all sample teeth were treated with 35 days of a remineralizing regimen which consist of 2% sodium fluoride and mixture of artificial saliva (Caphosol) and human saliva. Both post-remineralization images of DIFOTI and radiograph were taken. The DIFOTI and radiograph images before demineralization, demineralization and 5 weeks remineralization images were entered the EMAGO software for subtraction. McNemar's test of equality of paired proportions were used to analyze the data. At the end of the remineralization, the mineral content of the lesion were evaluated with microradiographs to compare before and after remineralization.;Results. 100% of the sample exhibited success with DIFOTI and failure with digital radiography at three weeks demineralization and the p-value was less than 0.001. 73% (22/30) exhibited success with DIFOTI and failure with digital radiography in the detection of remineralization; the other 27% exhibited failure with both procedures, the p-value was less than 0.001. DIFOTI was able to show statistically significant differences on detection of demineralization and remineralization compared with digital radiography using a subtraction program.;Conclusion. Since DIFOTI was able to show remineralization with the subtraction technique, therefore it can be used for monitoring carious lesions over time. A recommendation was made to use DIFOTI with digital subtraction as an adjunct tool in routine patient examination. With early caries detection, address risks factors, implement a preventive regimen early and monitor caries lesion over time are the current trend for caries management - that is "caries management by risk assessment" - CAMBRA.
机译:介绍。龋齿涉及羟基磷灰石牙齿结构的脱矿物质。但是,在空化之前,可以通过再矿化逆转该过程。龋病的早期发现和随着时间推移病灶的进展监测是该疾病管理中的关键因素。放射线照相术已成为常规近端龋齿检查的最常用工具。口腔放射成像是当前的诊断标准。引入了诸如数字成像光纤透射照明(DIFOTI)之类的设备,以改善龋齿病变的早期检测。该研究的目的是(1)确定数字成像光纤透射照明(DIFOTI)是否可以检测牙釉质近端病变处的再矿化; (2)使用数字减影结合两种成像方式,比较DIFOTI和数字X线照相术在牙釉质近端病变中脱矿质和再矿化的检测能力;材料和方法。在alpha = 0.025,beta = 80%时,三十对完整的人类前磨牙随机成对排列。在脱盐过程之前以及脱矿过程中,每周用DIFOTI和数字X射线照片拍摄牙齿样本图像,直到脱矿期间每周进行一次,直到用DIFOTI和数字X射线照片检测到脱矿为止。将样品组放入去矿物质溶液中,该溶液可模拟体内的去矿物质过程,该过程由37%的pH值为5的1%Carbopol C907溶液中的饱和羟基磷灰石/0.1 M乳酸组成。脱矿质完成后,所有牙齿均经过35天的再矿化方案处理,该方案包括2%的氟化钠以及人工唾液(Caphosol)和人唾液的混合物。同时拍摄了DIFOTI的再矿化图像和X射线照片。将脱矿质,脱矿质和5周再矿化之前的DIFOTI和X射线照片图像输入EMAGO软件进行减法。麦克尼尔(McNemar)的配对比例相等性检验用于分析数据。再矿化结束时,用射线照相术评估病变的矿物质含量,以比较再矿化前后的结果。 100%的样品在脱矿三周后显示成功使用DIFOTI,而在数字射线照相中显示失败,p值小于0.001。 73%(22/30)的DIFOTI成功,而数字X线照相术在再矿化检测中失败;其余27%的患者均在两种手术中均失败,p值小于0.001。与使用减法程序的数字射线照相相比,DIFOTI能够在脱矿质和再矿质的检测上显示出统计学上的显着差异。由于DIFOTI能够通过减法技术显示出矿化作用,因此可用于随时间监测龋齿病变。建议将带数字减法的DIFOTI用作常规患者检查的辅助工具。通过早期发现龋齿,解决风险因素,及早实施预防方案以及随着时间的推移监测龋齿病变是目前龋齿管理的趋势-即“通过风险评估进行龋齿管理”-CAMBRA。

著录项

  • 作者

    Chiang, Yu-Hsuen Jessica.;

  • 作者单位

    Tufts University School of Dental Medicine.;

  • 授予单位 Tufts University School of Dental Medicine.;
  • 学科 Health Sciences Dentistry.;Health Sciences Radiology.;Physics Optics.
  • 学位 M.S.
  • 年度 2009
  • 页码 70 p.
  • 总页数 70
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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