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Guided-mode resonance in planar photonic crystals: Application to sensing.

机译:平面光子晶体中的导模共振:在传感中的应用。

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摘要

This dissertation addresses the design, fabrication and characterization of planar photonic crystals that employ the guided-mode resonance effect for sensing and detection applications. A theoretical basis for these applications is first developed, followed by the demonstration of a near-ultraviolet reflectance filter that provides high reflection efficiency in the 400-450 nm spectral range. The response of photonic crystal label-free biosensors is shown to be greatly improved by the use of a near-ultraviolet device, and this improvement in performance is shown to stem from the enhanced surface sensitivity and lowered bulk sensitivity for devices operating in this wavelength range. The application of PCs for wavelength detection is demonstrated by developing a system employing a continuously variable reflectance filter. The system is composed of only two components and allows detection of wavelength changes as small as 0.011 nm. Visible wavelength PCs are also studied for application as fluorescence enhancement biosensors. For the first time, a PC capable of a dual enhancement modality (enhanced excitation and enhanced extraction of fluorescence) is demonstrated for boosting quantum dot fluorescence by over two orders of magnitude. The distance dependence of the enhanced excitation effect is studied and provides clarification for its mechanism and suggests that the PC can be modified to accommodate a wide range of analyte sizes. Finally the enhanced extraction effect is studied in detail using a model system involving quantum dots and waveguide gratings. The results suggest that enhanced extraction can greatly improve the output of fluorophores that are spectrally and spatially matched to the device. A practical demonstration of this effect is carried out in the detection of the cytokine TNF-alpha.
机译:本文致力于平面光子晶体的设计,制造和表征,该平面光子晶体采用导模共振效应进行传感和检测应用。首先开发了这些应用的理论基础,然后演示了近紫外反射滤光片,该滤光片在400-450 nm光谱范围内提供高反射效率。通过使用近紫外设备,可以显着改善无光子晶体标记生物传感器的响应,而性能的提高则归因于在此波长范围内工作的设备表面灵敏度的提高和体积灵敏度的降低。通过开发采用连续可变反射率滤光片的系统,可以证明PC在波长检测中的应用。该系统仅由两个组件组成,可以检测小至0.011 nm的波长变化。还研究了可见波长的PC作为荧光增强生物传感器的应用。首次展示了具有双重增强模式(增强的激发和增强的荧光提取)能力的PC,可将量子点荧光增强两个数量级以上。研究了增强的激发效应的距离依赖性,并澄清了其机理,并建议可以对PC进行改造,以适应各种分析物尺寸。最后,使用包含量子点和波导光栅的模型系统详细研究了增强的提取效果。结果表明,增强的提取可以大大提高在光谱上和空间上与设备匹配的荧光团的输出。在检测细胞因子TNF-α中进行了这种效果的实际证明。

著录项

  • 作者

    Ganesh, Nikhil.;

  • 作者单位

    University of Illinois at Urbana-Champaign.;

  • 授予单位 University of Illinois at Urbana-Champaign.;
  • 学科 Engineering Materials Science.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 143 p.
  • 总页数 143
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 工程材料学;
  • 关键词

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