首页> 外文学位 >Lengthening at the sites of fixation and an increase in anterior laxity following anterior cruciate ligament reconstruction: An in vivo study using Roentgen stereophotogrammetric analysis.
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Lengthening at the sites of fixation and an increase in anterior laxity following anterior cruciate ligament reconstruction: An in vivo study using Roentgen stereophotogrammetric analysis.

机译:前十字韧带重建后固定位点的延长和前松弛的增加:一项使用伦琴立体摄影测量分析的体内研究。

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摘要

Increases in anterior laxity occur following anterior cruciate ligament (ACL) reconstruction caused by an increase in length of the graft-fixation-bone-construct. A millimeter-for-millimeter relation exists between the increase in length of the graft-fixation-bone-construct and an increase in anterior laxity in vitro; however, in vivo the relation remains controversial because other factors such as biological healing might increase the stiffness and decrease the contribution to anterior laxity. Because lengthening at the sites of fixation could cause an increase in anterior laxity, the primary objectives of this dissertation were (1) to develop and validate methods to measure lengthening at the sites of fixation and the increase in anterior laxity and (2) to apply these methods in an in vivo study to determine whether the increase in anterior laxity following ACL reconstruction is caused by lengthening at the sites of fixation. To satisfy these objectives, Roentgen stereophotogrammetric analysis (RSA) was used to measure the lengthening at the sites of fixation and the increase in anterior laxity. For the first objective, tantalum markers were implanted into the bones, graft, and fixation devices during ACL reconstruction on 6 cadaveric legs. The knees were cyclically loaded in the anterior-posterior direction for 1500 cycles and both the lengthening at the sites of fixation and the increase in anterior laxity were measured. Because the lengthening at the sites of fixation and the increase in anterior laxity were determined successfully using RSA in vitro, similar methods were used in an in vivo longitudinal study. Nineteen subjects were treated with a soft-tissue allograft and slippage-resistant fixation. Tantalum markers were injected into the bones, graft, and fixation devices. On the day of surgery and at 1, 2, 3, 4, 6, and 12 months, RSA was used to measure lengthening at the sites of fixation and the increase in anterior laxity. It was determined that although lengthening at the sites of fixation did occur, it was not related to the increase in anterior laxity and that it was offset by an increase in stiffness at the sites of fixation most likely due to biological healing of the graft into the tunnel wall.
机译:在前交叉韧带(ACL)重建后,由于移植物固定骨结构长度的增加而导致前松弛的增加。移植物固定骨结构的长度增加与体外前松弛度增加之间存在毫米对毫米的关系。然而,在体内这种关系仍然存在争议,因为其他因素(例如生物修复)可能会增加硬度并降低对前松弛的贡献。由于在固定部位的延长可能会导致前松弛的增加,因此本论文的主要目标是(1)开发并验证测量固定部位的伸长和前松弛的增加的方法,以及(2)应用这些方法在体内研究中确定ACL重建后前松弛的增加是否是由于固定部位的延长引起的。为了满足这些目的,使用了伦琴立体摄影测量分析(RSA)来测量固定部位的长度和前松弛度的增加。为了第一个目标,在6具尸体腿的ACL重建过程中,将钽标记物植入骨骼,移植物和固定装置中。膝盖在前后方向上循环加载1500个循环,并测量了固定位点的拉长和前松弛度的增加。由于使用RSA在体外成功确定了固定部位的延长和前松弛的增加,因此在体内纵向研究中使用了类似的方法。 19名受试者接受了软组织同种异体移植和抗滑固定。钽标记物被注入骨骼,移植物和固定装置中。在手术当天以及1、2、3、4、6和12个月时,使用RSA来测量固定部位的长度和前松弛度的增加。确定的是,尽管确实发生了固定部位的延长,但这与前松弛度的增加无关,并且被固定部位的刚度增加所抵消,这很可能是由于将移植物生物学修复到固定部位而引起的。隧道墙。

著录项

  • 作者

    Smith, Conrad Kay.;

  • 作者单位

    University of California, Davis.;

  • 授予单位 University of California, Davis.;
  • 学科 Engineering Biomedical.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 110 p.
  • 总页数 110
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-17 11:38:20

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