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In Vitro Evaluations of Hexokinase-2 Inhibition with 3-Bromopyruvate Encapsulated in Targeted Liposomal Formulations using 3D Spheroid Models of Tumor Aerobic Glycolysis

机译：用肿瘤有氧糖醇的3D球状模型包封3-溴吡合他分用3-溴吡合他分包封的六酮酶-2抑制的体外评价

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作者
Gandham, Srujan Kumar.;
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作者单位

Northeastern University.;

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授予单位 Northeastern University.;
学科
学位 M.S.
年度 2014
页码 79 p.
总页数 79
原文格式 PDF
正文语种 eng
中图分类 AAI10133322;
关键词
3-bromopyruvate; EGFR peptide; Liposomal formulations; SKOV-3; Spheroid models; Tumor glycolysis; Tumors;

机译：3-溴吡合金;EGFR肽;脂质体配方;skov-3;球形模型;肿瘤糖酵解;肿瘤;

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专利

1. Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis [J] . Srujan Kumar Gandham, Meghna Talekar, Amit Singh, International Journal of Nanomedicine . 2015,第1期

机译：靶向性3-溴丙酮酸脂质体对己糖激酶-2的抑制作用在好氧糖酵解的卵巢肿瘤球体模型中
2. Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis [J] . Zhang Yinlong, Wei Jingyan, Xu Jiaqi, ACS applied materials & interfaces . 2018,第3期

机译：脂质体纳米粒子介导的有氧糖溶解抑制肿瘤能量供应
3. Targeted AKT Inhibition in Prostate Cancer Cells and Spheroids Reduces Aerobic Glycolysis and Generation of Hyperpolarized [1- 13 C] Lactate [J] . Sui Seng Tee, Izabela Suster, Steven Truong, Molecular cancer research: MCR . 2018,第3期

机译：前列腺癌细胞和球状体中的靶向AKT抑制可减少有氧糖酵解和超积极化[1-13 c]乳酸的产生
4. Directing the self-assembly of tumor spheroids within 3D bioprinted cellular heterogeneous in vitro models [C] . Tao Jiang, Jose Gil Munguia-Lopez, Joel Grant, Society for Biomaterials annual meeting and exposition . 2017

机译：指导3D生物打印细胞异质体外模型中肿瘤球体的自组装
5. HIF-1alpha Activation in 3D Tumor Spheroids and Evaluation of 2-Methoxyestradiol Therapy using Targeted Nanoparticle Formulations. [D] . Raikar, Ankita. 2013

机译：在3D肿瘤球体中的HIF-1alpha激活和使用靶向纳米粒子制剂对2-甲氧基雌二醇治疗的评估。
6. Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis [O] . Srujan Kumar Gandham, Meghna Talekar, Amit Singh, 2015

机译：靶向性3-溴丙酮酸脂质体对己糖激酶-2的抑制作用在好氧糖酵解的卵巢肿瘤球体模型中
7. In vitro evaluations of hexokinase-2 inhibition with 3-bromopyruvate encapsulated in targeted liposomal formulations using 3D spheroid models of tumor aerobic glycolysis [O] . Srujan Kumar Gandham -1

机译：用肿瘤有氧糖醇的3D球状模型包封3-溴吡合他分用3-溴吡合他分包封的六酮酶-2抑制的体外评价

In Vitro Evaluations of Hexokinase-2 Inhibition with 3-Bromopyruvate Encapsulated in Targeted Liposomal Formulations using 3D Spheroid Models of Tumor Aerobic Glycolysis

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