In this research, a kind of amphiphilic compound: 2-hydroxymethyl-[1,4,7,10,13-pentaoxa benzo cyclo pentadecane]-3,4,5-tris[4-(10-dodecyl-l-oxo)benzyloxy]benzoate was synthesized by methyl p-hydroxybenzoate, 4-carbonate benzo-15-crown-5 and other reagents. The chemical composition and structure were characterized by FT-IR, 1H NMR, MS, DSC and POM. Then, the ion channel membrane was obtained from grafting this new kind of crown ether compound to the surface of polycarbonate track-etched membrane by the method of ultraviolet (UV) light grafting. The grafting volume is: 606 μg/cm2. The ion channel membrane was characterized by the method of ATR, SEM and AFM. The results confirmed that the compound had successfully grafted onto the surface of the polycarbonate track-etched membrane, and formed a dense layer by the self-assembly columnar structures. At last, the ion channel function of the membrane was determined by self-designed membrane transport instrument. The ion transport rate: PFM= 20.62 × 10-6cm/s. The separation factor of ion channel membrane and controlled membrane: αFM/NFM=5.96. These data confirmed that the ion channel membrane can selectively recognize and transport Na+. It is a new type ofNa+ recognized ion channel membrane.%采用对羟基苯甲酸甲酯、4-羧基苯并-15-冠醚-5等物质为原料制备了具有自组装功能的两亲性冠醚化合物 2-羟甲基-[1,4,7,10,13-苯并15冠5]-3,4,5-三[4-(10-十二烷基-1-羰基)苄氧基]苯甲酸,采用 FT-IR,1H NMR,MS,DSC 以及POM 等方法对其化学结构和结晶性能进行表征.利用紫外光接枝法将制得的冠醚化合物接枝到聚碳酸酯核孔膜表面构筑了离子通道膜,接枝量为 606 μg/cm2.采用 ATR-FTIR 和 XPS 分析离子通道膜的表面元素组成和化学键合情况,SEM 和 AFM 用于检测离子通道膜表面和断面的微观结构.结果表明,这种两亲性冠醚化合物在核孔膜的表面自行组装形成了由大量柱状结构组成的致密皮层.利用实验室自制的膜运输装置对离子传输性能进行了测评,离子通道膜平均离子通过效率 PFM=20.62×10-6 cm/s,对比膜与其的分离系数αFM/NFM=5.96,数据证实合成的两亲性冠醚化合物能特异性地识别和运输 Na+,由其制得的离子通道膜是一种 Na+ 识别型离子通道膜.
展开▼
