General office building in Nanjing Pharmaceutical Co., Ltd is a reinforced concrete frame building which is reconstructed from a reinforced concrete bent structure. Based on the strengthening and reconstruction project, some key problems in strengthening and reconstruction design of the bent frame structure, including methods of testing and appraisement, computing and analyzing, foundation reinforcement, concrete members reinforcement and seismic reinforcement, etc. Some effective methods are introduced to solve the problems.%南京医药总部办公楼为单层钢筋混凝土排架结构厂房,通过加固改造后成为双层钢筋混凝土框架结构.结合实例讨论钢筋混凝土工业厂房改变结构体系时考虑的检测鉴定、计算分析、基础加固、混凝土构件加固及抗震构造加固等关键问题,介绍一些有效的解决办法.
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