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首页> 中文期刊> 《亚太热带生物医学杂志（英文版）》 >Plant-derived anticancer agents: A green anticancer approach

Plant-derived anticancer agents: A green anticancer approach

         
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摘要

Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure.Plants are reservoirs for novel chemical entities and provide a promising line for research on cancer.Hitherto,being effective,chemotherapy is accompanied by certain unbearable side effects.Nevertheless,plants and plant derived products is a revolutionizing field as these are Simple,safer,ecofriendly,low-cost,fast,and less toxic as compared with conventional treatment methods.Phytochemicals are selective in their functions and acts specifically on tumor cells without affecting normal cells.Carcinogenesis is complex phenomena that involves many signaling cascades.Phytochemicals are considered suitable candidates for anticancer drug development due to their pleiotropic actions on target events with multiple manners.The research is in progress for developing potential candidates (those can block or slow down the growth of cancer cells without any side effects) from these phytochemicals.Many phytochemicals and their derived analogs have been identified as potential candidates for anticancer therapy.Effort has been made through this comprehensive review to highlight the recent developments and milestones achieved in cancer therapies using phytomolecules with their mechanism of action on nuclear and cellular factors.Furthermore,drags for cancer treatment and their limitations have also been discussed.

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  • 来源
    《亚太热带生物医学杂志（英文版）》 |2017年第12期|1129-1150|共22页
  • 作者

    Javed Iqbal; Banzeer Ahsan Abbasi; Tariq Mahmood; Sobia Kanwal; Barkat Ali; Sayed Afzal Shah; Ali Talha Khalil;

  • 作者单位

    Department of Plant Sciences,Quaid-i-Azam University Islamabad,45320,Pakistan;

    Department of Plant Sciences,Quaid-i-Azam University Islamabad,45320,Pakistan;

    Department of Plant Sciences,Quaid-i-Azam University Islamabad,45320,Pakistan;

    Department of Zoology,University of Gujrat,Sub Campus Rawalpindi,Pakistan;

    Department of Plant Sciences,Quaid-i-Azam University Islamabad,45320,Pakistan;

    Department of Plant Sciences,Quaid-i-Azam University Islamabad,45320,Pakistan;

    Department of Eastern Medicine and Surgery,Qarshi University,Lahore,Pakistan;

    UNESCO UNISA Africa chair in nanoscience and nanotechnology,South Africa;

    Nanosciences African Network(NANOAFNET),South Africa;

  • 原文格式 PDF
  • 正文语种 eng
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