Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Hussein Farhan; Hassan Rammal; Akram Hijazi; Ahmad Daher; Mohamad Reda; Hussein Annan; Ali Chokr; Ali Bassal; Bassam Badran

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Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

机译：黎巴嫩植物大戟（Euphorbia macroclada schyzoceras）的化学成分和抗氧化活性

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Objective:To determine the chemical composition, total phenolic and total flavonoid contents of the crude extracts from leaves and stems of a Lebanese plant Euphorbia macroclada schyzoceras (E. macroclada), and to evaluate their antioxidant potential using DPPH, H2O2, and chelating of ferrous ions tests. Methods:Quantification of the total phenolic and total flavonoid contents of the crude extracts from leaves and stems and the antioxidant activities were evaluated using spectrophotometric analyses. The chemical composition has been estimated using different techniques such as IR, LC/MS and NMR. Results:Ethanolic extract from leaves of E. macroclada was better than aqueous extract and showed higher content in total phenolic and total flavonoid than found in the stems. On the other hand, using DPPH and H2O2 tests, this extract from leaves showed higher antioxidant capacity than aqueous extract. However, using the chelating of ferrous ions test, the antioxidant activity of the aqueous extract of both stems and leaves was stronger than that of ethanolic once. The chemical composition of the whole plant showed the presence of some aromatic compounds and fatty acids. Conclusions:Both ethanolic and water extracts from both parts of this plant are effective and have good antioxidant power. So, this plant can be used in the prevention of a number of diseases related to oxidative stress.

机译：目的：测定黎巴嫩植物大戟（Euphorbia macroclada schyzoceras）（E. macroclada）叶片和茎中粗提物的化学成分，总酚和总黄酮含量，并使用DPPH，H2O2和亚铁螯合法评估其抗氧化能力离子测试。方法：采用分光光度法对叶和茎粗提物中的总酚和总黄酮含量进行定量，并评估其抗氧化活性。已使用不同的技术（例如IR，LC / MS和NMR）估算了化学成分。结果：大叶蝉叶片的乙醇提取物优于水提取物，并且总酚和总黄酮的含量高于茎中的含量。另一方面，使用DPPH和H2O2测试，这种叶提取物的抗氧化能力比水提取物高。然而，使用亚铁离子螯合试验，茎和叶的水提物的抗氧化活性都比乙醇一次强。整个植物的化学成分表明存在一些芳香族化合物和脂肪酸。结论：该植物两部分的乙醇和水提取物均有效且具有良好的抗氧化能力。因此，该植物可用于预防许多与氧化应激有关的疾病。

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《亚太热带生物医学杂志（英文版）》 |2013年第7期|542-548|共7页
作者
Hussein Farhan; Hassan Rammal; Akram Hijazi; Ahmad Daher; Mohamad Reda; Hussein Annan; Ali Chokr; Ali Bassal; Bassam Badran;
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Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

Faculty of Agricultural and Veterinary Sciences,Lebanese University, Lebanon;

Doctoral School of Science and Technology, Research Platform for Environmental Science, Lebanese University, Lebanon;

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Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

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