Antimicrobial susceptibility patterns of Streptococcus pneumoniae over 6 years at Gondar University Hospital, Northwest Ethiopia

Belay Anagaw; Chandrashekhar Unakal; Mucheye Gezachew; Fantahun Biadgelgene; Berhanu Anagaw; Tariku Geleshe; Birke Taddese; Birhanu Getie; Mengistu Endris; Andargachew Mulu

首页> 外文期刊>亚太热带生物医学杂志（英文版） >Antimicrobial susceptibility patterns of Streptococcus pneumoniae over 6 years at Gondar University Hospital, Northwest Ethiopia

【24h】

Antimicrobial susceptibility patterns of Streptococcus pneumoniae over 6 years at Gondar University Hospital, Northwest Ethiopia

机译：埃塞俄比亚西北部贡德尔大学医院超过6年的肺炎链球菌耐药性模式

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Objective:To assess the magnitude and antimicrobial susceptibility patterns of Streptococcus pneumoniae isolates from various clinical specimens. Methods:A record based on retrospective study was conducted at Gondar University Teaching Hospital from September 2007 to January 2012. All patients who visited Gondar University Hospital and provided clinical specimens (body fluids, discharge, swab and blood) for routine bacteriological culturing and antimicrobial susceptibility testing were taken for analysis. Clinical specimens were processed for bacterial culture according to the standard procedures. Antimicrobial susceptibility test for isolated organisms was done using agar disk diffusion method. The data were entered and analyzed using SPSS software version 16 package. Results: One hundred and fifty three Streptococcus pneumoniae were isolated from patients who visited Gondar University Teaching Hospital bacteriology laboratory for culture. Majority of the pneumococcal isolates were from inpatients [111(72.5%)], and 74(48.4%) were from body fluids. Out of the total isolates, 93(61%) were found to be resistant to at least one antibiotic used for susceptibility testing. Forty eight (43.2%) of the isolates were multi-drug resistant (resistant to two or more drugs). The resistance rate noted for both ciprofloxacin 17(11.1%) and ceftriaxone 15(9.8%) were alarming. Conclusions: High proportions of the isolates tend to be increasingly resistant to the commonly prescribed drugs. The recommended drug of choice like ciprofloxacin and ceftriaxone were found to be less susceptible in the study area. Based on the findings, we therefore recommend that antimicrobial agents should be inspected for acceptable activity before they are prescribed and administered empirically. Further study with a better design and survey of antimicrobial susceptibility at large scale shoule be performed to draw advanced information.

机译：目的：评估各种临床标本中肺炎链球菌分离物的数量和耐药性。方法：从2007年9月至2012年1月，在Gondar大学教学医院进行回顾性研究。所有来Gondar University Hospital并提供临床标本（体液，分泌物，拭子和血液）以进行常规细菌培养和抗菌药敏性的患者。测试进行分析。根据标准程序对临床标本进行细菌培养。使用琼脂圆盘扩散法对分离出的微生物进行了药敏试验。使用SPSS 16版软件包输入并分析数据。结果：从访问Gondar大学教学医院细菌学实验室进行培养的患者中分离出了153个肺炎链球菌。肺炎球菌的大多数分离物来自住院病人[111（72.5％）]，而74（48.4％）来自体液。在所有分离株中，有93个（61％）对至少一种用于药敏试验的抗生素具有抗药性。分离株中有四十八（43.2％）种具有多重耐药性（对两种或多种药物有耐药性）。环丙沙星17（11.1％）和头孢曲松15（9.8％）的耐药率令人震惊。结论：高比例的分离株倾向于对常用处方药产生越来越大的抵抗力。在研究区域发现推荐的推荐药物如环丙沙星和头孢曲松不易感染。因此，基于这些发现，我们建议在进行处方和经验性使用之前应检查抗菌剂的可接受活性。为了更好地设计和研究抗菌素的敏感性，应进行大规模研究以获取先进的信息。

著录项

来源
《亚太热带生物医学杂志（英文版）》 |2013年第7期|536-541|共6页
作者
Belay Anagaw; Chandrashekhar Unakal; Mucheye Gezachew; Fantahun Biadgelgene; Berhanu Anagaw; Tariku Geleshe; Birke Taddese; Birhanu Getie; Mengistu Endris; Andargachew Mulu;
展开▼
作者单位

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Ethiopia;

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Ethiopia;

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Ethiopia;

Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia;

Science Faculty, Addis Ababa University, Addis Ababa, Ethiopia;

College of Medicine and Health Sciences, University of Gondar Teaching Hospital Laboratory, Bacteriology Section, University of Gondar, Ethiopia;

College of Medicine and Health Sciences, University of Gondar Teaching Hospital Laboratory, Bacteriology Section, University of Gondar, Ethiopia;

College of Medicine and Health Sciences, University of Gondar Teaching Hospital Laboratory, Bacteriology Section, University of Gondar, Ethiopia;

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Ethiopia;

Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Ethiopia;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

Antimicrobial susceptibility patterns of Streptococcus pneumoniae over 6 years at Gondar University Hospital, Northwest Ethiopia

摘要

著录项

相关主题

期刊订阅