Laboratory assessment of the molluscicidal and cercariacidal activities of Balanites aegyptiaca

Eshetu Molla; Mirutse Giday; Berhanu Erko

摘要

Objective: To assess the molluscicidal and cercariacidal activities of aqueous extracts ofBalanites aegyptiaca (B. aegyptiaca) against Ethiopian Biomphalaria pfeifferi (B. pfeifferi), Lymnaea natalensis (L. natalensis) and Schistosoma mansoni (S. mansoni) cercariae. Methods:Extracts of seeds, endocarp, mesocarp, and fruit of B. aegyptiaca were tested for their activities against adult B. pfeifferi and L. natalensis. The cercariacidal activity of the seeds of the plant was also evaluated against S. mansoni. Bioassays were carried out following the methods recommended by WHO. Snail mortalities were compared between each plant part and snail species, and LC50 and LC90 values for the plant parts tested were computed. The cercariacidal activity of the plant was assessed by exposing the mice to the cercariae pre-exposed to aqueous extract of B. aegyptiaca seeds. Results:For the molluscicidal activities of seeds, endocarp, mesocarp and whole fruit, the LC50 values against B. pfeifferi were 56.32, 77.53, 65.51 and 66.63 mg/L, respectively, while the respective LC90 values were 77.70, 120.04, 89.50 and 97.55 mg/L. Similarly, the LC50 values for the seeds, endocarp, mesocarp and whole fruit against L. natalensis were 80.33, 92.61, 83.52 and 87.84 mg/L, respectively, while the respective LC90 values were 102.30, 138.21, 115.42 and 127.69 mg/L. B. pfeifferi were found to be more susceptible to B. aegyptiaca than L. natalensis. S. mansoni cercariae exposed to 15 mg/L of extract of seeds were incapable of infecting mice. The mean egg load of tissue was reduced in mice infected with the cercariae exposed to 5 and 10 mg/L of the extract. Conclusions:The aqueous extracts of different parts of B. aegyptiaca exhibited reasonable molluscicidal activity against B. pfeifferi and L. natalensis, as well as cercariacidal activity against S. mansoni cercariae. However, comprehensive laboratory evaluation is recommended prior to field tests of the plant parts since their impact on other aquatic biota is not known.

机译：目的：评估Balanites aegyptiaca（B. aegyptiaca）的水提物对埃塞俄比亚Biomphalaria pfeifferi（B. pfeifferi），Lymnaea natalensis（L. natalensis）和Mansoni（S. mansoni）cerceriacidal活性的评估。方法：检测埃及埃及芽孢杆菌的种子，内果皮，中果皮和果实提取物对成虫B. pfeifferi和L. natalensis的活性。还评估了植物种子对曼氏链球菌的抗酸活性。按照WHO推荐的方法进行生物测定。比较了每个植物部位和蜗牛种类的蜗牛死亡率，并计算了所测试植物部位的LC50和LC90值。通过将小鼠暴露于预先暴露于埃及双歧杆菌种子的水提取物中的尾c中来评估植物的尾酸活性。结果：就种子，内果皮，中果皮和整个果实的杀软体动物活性而言，对费氏芽孢杆菌的LC50值分别为56.32、77.53、65.51和66.63 mg / L，而LC90值分别为77.70、120.04， 89.50和97.55 mg / L。同样，种子，内果皮，中果皮和整果对纳塔尔纳豆的LC50值分别为80.33、92.61、83.52和87.84 mg / L，而LC90分别为102.30、138.21、115.42和127.69 mg / L。人们发现，比起纳塔氏乳杆菌，pfeifferi B. pfeifferi更容易受到埃及伊蚊B. aegyptiaca感染。暴露于15 mg / L种子提取物的曼氏链球菌不能感染小鼠。在暴露于5和10 mg / L提取物的尾c感染的小鼠中，组织的平均卵负荷降低。结论：埃及埃塞俄比亚不同部位的水提物对pfeifferi和L. natalensis具有合理的杀灭软体动物的活性，以及对曼氏尾S的酿酒酵母酸活性。但是，建议在对植物部位进行现场测试之前进行全面的实验室评估，因为尚不清楚它们对其他水生生物的影响。

Laboratory assessment of the molluscicidal and cercariacidal activities of Balanites aegyptiaca

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