Evaluation of larvicidal activity of Pongamia pinnata extracts against three mosquito vectors

Guna Ranjan Kolli; Balakrishnan; Vijayan; Raja Sundararajan

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Evaluation of larvicidal activity of Pongamia pinnata extracts against three mosquito vectors

机译：樟子松提取物对三种蚊媒杀幼虫活性的评估

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Objective: To evaluate the mosquito larvicidal activity of Pongamia pinnata (P. pinnata) extracts against three mosquito vectors.Methods:The larval mortality was found in both methanol and hydroalcohol extracts of P. pinnata against fourth instar larvae of Culex quinquefasciatus, Aedes aegypti and Anopheles stephensi. The mortality was observed 24 h and 48 h after treatment, data was subjected to probit analysis to determine lethal concentration (LC50 and LC90) to kill 50 and 90 percent of treated larvae of tested species.Results:The methanol and hydroalcohol extracts of bark part of P. pinnata L were tested against Culex quinquefasciatus, Aedes aegypti and Anopheles stephensi with LC50 values of 84.8, 118.2 and 151.7 ppm; 97.7, 128.3 and 513 ppm. The highest larval mortality was found in methanol extract of P. pinnata when comparable to the hydroalcohol extract.Conclusions:These results suggest that both methanol and hyrdoalcohol extracts have the potential to be used as an ideal ecofriendly approach for the control of disease vectors. This could lead to isolation of novel natural larvicidal compounds.

机译：目的：评价Pongamia pinnata（P. pinnata）提取物对三种灭蚊载体的灭蚊活性。方法：P。pinnata甲醇和水醇提取物中的幼虫死亡率均对Culex quinquefasciatus，埃及伊蚊和四龄幼虫的杀灭作用。斯蒂芬按蚊。在处理后24小时和48小时观察死亡率，对数据进行概率分析以确定致死浓度（LC50和LC90），以杀死50％和90％的被处理物种的幼虫。结果：树皮部分的甲醇和水醇提取物测试了P. pinnata L的抗库蚊，埃及伊蚊和斯蒂芬按蚊的LC50值分别为84.8、118.2和151.7 ppm; 97.7、128.3和513 ppm。与水醇提取物相比，P.pinnata甲醇提取物中的幼虫死亡率最高。结论：这些结果表明，甲醇和水醇提取物都有可能被用作理想的生态友好方法来控制病媒。这可能导致分离出新的天然杀幼虫化合物。

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《亚太热带生物医学杂志（英文版）》 |2013年第11期|853-858|共6页
作者
Guna Ranjan Kolli; Balakrishnan; Vijayan; Raja Sundararajan;
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GITAM Institute of Pharmacy, GITAM University, Vishakapatnam-530017, Andrapradesh, India;

National Centre for Disease Control, Formely Southern India Branch, NICD Coonoor-643101, Tamil Nadu, India;

Department of Pharmaceutical Biotechnology, J.S.S College of Pharmacy, Rocklands, P.B No.20 0otacamund 643001, India;

GITAM Institute of Pharmacy, GITAM University, Vishakapatnam-530017, Andrapradesh, India;

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Evaluation of larvicidal activity of Pongamia pinnata extracts against three mosquito vectors

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