From control to eradication of malaria:the end of being stuck in second gear?

Khadjavi Amina; Giribaldi Giuliana; Prato Mauro

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From control to eradication of malaria:the end of being stuck in second gear?

机译：从控制到消除疟疾：被困在第二档的终结？

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More than 2 billion people are at risk of malaria, which primarily affects poor populations in tropical and subtropical areas, including Southern Asia. As malaria incidence has been reduced strongly in some parts of endemic regions by combinations of interventions, including artemisinin-based therapies and insecticide-treated bed nets, a new goal has been established recently by charity foundations which support research on malaria:the worldwide eradication of the pathology. Doing away with control approaches which have been applied for the last 50 years and more focus on elimination objectives will deeply change priorities in the area of malaria treatment, chemoprevention, vector control, vaccine research and health system assessment. In this review, actual knowledge on pathogenesis and pharmacology is discussed, and new drugs, vaccines and insecticides are described.

机译：超过20亿人面临疟疾风险，这主要影响包括南亚在内的热带和亚热带地区的贫困人口。由于结合了多种干预措施，包括基于青蒿素的疗法和经杀虫剂处理的蚊帐，大大减少了流行地区的疟疾发病率，慈善基金会最近建立了一个新的目标，以支持疟疾的研究：在世界范围内根除疟疾病理学。取消过去50年来一直采用的控制方法，更多地关注消除目标，将深刻改变疟疾治疗，化学预防，病媒控制，疫苗研究和卫生系统评估领域的重点。在这篇综述中，讨论了有关发病机理和药理学的实际知识，并描述了新药，疫苗和杀虫剂。

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《亚太热带医药杂志（英文版）》 |2010年第005期|412-420|共9页
作者
Khadjavi Amina; Giribaldi Giuliana; Prato Mauro;
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Department of Genetics, Biology and Biochemistry, University of Torino Medical School, 10126, Torino, Italy;

Department of Genetics, Biology and Biochemistry, University of Torino Medical School, 10126, Torino, Italy;

Department of Genetics, Biology and Biochemistry, University of Torino Medical School, 10126, Torino, Italy;

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From control to eradication of malaria:the end of being stuck in second gear?

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