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首页> 外文期刊>亚太热带医药杂志（英文版） >Effects of ethanol extract of leaves of Helianthus annus on the fecundity of Wistar rats
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Effects of ethanol extract of leaves of Helianthus annus on the fecundity of Wistar rats

机译：向日葵叶片乙醇提取物对Wistar大鼠生殖力的影响

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Objective:To evaluate the effects of ethanol extract of leaves of Helianthus annus (H. annus) on the fecundity of Wistar rats. Methods:Forty (20 male and 20 female) Wistar rats, grouped into control, ethanol extract treated rats and untreated, were used for the study. Treated rats had 0.5 g/kg of ethanol extract orally for 2 weeks;control rats had 5%alcoholic water (solvent);and untreated rats had their normal feed and clean drinking water. Following treatment, the animals were sub-grouped into 5 mating groups to observe the coital frequency, pregnancy rate and average number of pups per group in pairs. Results:The results showed that coital frequency was unaffected by the extract treatment but pregnancy rate and number of pups per rat and per group were reduced significantly in groups II, III and IV compared to those of group I and V rats which were not treated with the ethanol extract of leaves of H. annus. Conclusions:The histo-degenerative in the gonads reportedly induced by this ethanol extract in previous studies may be responsible for the reduced fecundity observed in treated adult rats.
机译：目的：评价向日葵叶片乙醇提取物对Wistar大鼠生殖能力的影响。方法：采用Wistar大鼠40只（雄性20只，雌性20只），分为对照组，乙醇提取物处理组和未处理组。处理的大鼠口服乙醇提取物0.5 g / kg，持续2周;对照组的大鼠饮用5％的酒精水（溶剂）;未经处理的大鼠则具有正常的饲料和清洁的饮用水。治疗后，将动物分为5个交配组，以成对观察每组的性交频率，妊娠率和幼崽的平均数量。结果：结果表明，与未经I / V处理的I和V组相比，提取物处理对性交频率没有影响，但是II，III和IV组的怀孕率和每只大鼠和每组的幼仔数显着降低。黄花树叶的乙醇提取物。结论：在以前的研究中据报道，这种乙醇提取物在性腺中引起组织变性，可能是治疗成年大鼠生殖力降低的原因。

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